ArticleThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2025
The role of the EASIX score in patients with hypertension: a cross-sectional study.
Article in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- EASIX and Arterial stiffness in relation to nocturnal blood pressure patterns in newly diagnosed hypertension.Journal of human hypertension · 2026Article
- Prognostic value of the endothelial activation and stress index (EASIX) for in-hospital and overall mortality in patients undergoing transcatheter aortic valve implantation.BMC cardiovascular disorders · 2026Article
- Endothelial Activation and Stress Index Predicts Poor Coronary Collateral Development in Chronic Total Occlusion.Journal of cardiovascular development and disease · 2026Article
- Association of the Endothelial Activation and Stress Index with Mortality in Critically Ill Patients with Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study.International journal of chronic obstructive pulmonary disease · 2026Article
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12 authors.
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Abstract
backgroundHypertension (HTN) remains a major global health problem, and inadequate blood pressure (BP) control contributes substantially to cardiovascular risk. The endothelial activation and stress index (EASIX), derived from routine laboratory parameters, has been proposed as a marker of vascular stress. Existing studies in hypertensive populations relied on office BP measurements and included patients with multiple comorbidities. This study evaluated the association between EASIX and 24-h ambulatory BP monitoring (ABPM) in a homogeneous cohort with isolated primary HTN.
methodsThis retrospective cross-sectional study included 192 adults aged 18-70 years diagnosed with HTN and undergoing 24-h ABPM. Patients were categorized into controlled and uncontrolled BP groups according to 24-h, daytime, and nighttime ABPM thresholds defined by the 2024 European Society of Cardiology guideline. The EASIX score was calculated as [lactate dehydrogenase × creatinine]/platelets and log
resultsThe EASIX score was significantly higher in the uncontrolled BP group than in the controlled BP group. Logistic regression identified ascending aortic diameter, serum sodium, serum albumin, and log
conclusionsEASIX demonstrated good discriminative performance for identifying hypertensive patients with inadequate BP control on ABPM. These findings suggest its potential role in risk stratification, warranting validation in prospective studies.
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