ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026
Radiofrequency Echographic Multi Spectrometry (REMS) for the evaluation of bone health in systemic lupus erythematosus (SLE).
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- REMS versus DXA in older adults: diagnostic concordance for osteoporosis in a geriatric outpatient population.Archives of osteoporosis · 2026Article
- Methodological Clarification and Analysis of Demographic and Anthropometric Determinants in the Calculation of REMS Bone Mineral Density.Calcified tissue international · 2026Article
- Comparative longitudinal assessment of bone mineral density measured with radiofrequency echographic multi-spectrometry (REMS) and dual X-ray absorptiometry (DXA) in a cohort of peritoneal dialysis patients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Letter comments on: Radiofrequency Echographic Multi Spectrometry (REMS) for the evaluation of bone health in systemic lupus erythematosus (SLE).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Clarifying clinically treatment-naive status for osteoporosis patients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Review
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11 authors.
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Abstract
The aim of this study was to evaluate the agreement between DXA and REMS in a cohort of SLE patients. REMS and DXA showed a fair to moderate agreement on osteoporosis diagnosis, with a similar ability to identify fracture risk. REMS tended to show lower bone mineral density and was more influenced by patients' demographics.
backgroundThe aim of this study was to assess the diagnostic agreement between Radiofrequency Echographic Multi Spectrometry (REMS) and dual-energy X-ray absorptiometry (DXA) for bone mineral density (BMD) in patients with systemic lupus erythematosus (SLE), particularly those receiving glucocorticoids (GCs).
methodsOne hundred-six SLE patients (44 GC-treated) underwent BMD assessment at the lumbar spine (LS), femoral neck (FN), and total hip (TH) using both DXA and REMS. We compared BMD and T-scores between methods and analyzed diagnostic agreement using linear regression, Cohen's kappa and Bland-Altman analysis. Receiver operator characteristic (ROC) curves evaluated the ability of REMS and DXA to discriminate fracture status.
resultsBMD measurements at all sites were significantly lower with REMS when compared with DXA across all skeletal sites (p < 0.001). Agreement in osteoporosis classification was slight to moderate (κ ranging from 0.229 at LS in all patients to 0.549 at FN in GC-treated patients). REMS showed moderate correlation with DXA and demonstrated 45% sensitivity and 88.4% specificity for diagnosing osteoporosis. Both REMS and DXA identified significant BMD differences between patients with and without vertebral fractures across all sites. ROC analysis revealed similar discriminative ability for fracture risk between REMS and DXA. REMS BMD values were more strongly associated with age, sex, and body mass index.
conclusionREMS and DXA showed a fair to moderate agreement in osteoporosis diagnosis and in fracture discrimination in SLE patients. While REMS appears a supportive tool in this setting, particularly in GC-treated individuals, further longitudinal studies are warranted to validate its predictive value and clinical utility.
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