Evidence map›Paper›PMID 41444823›Full record

ArticleCommunications biology2025

Continent-wide view of genomic diversity and divergence in the wolves of Asia.

Lauren M Hennelly, Bárbara R Parreira, Ash Noble, Camilla H Scharff-Olsen, M Çisel Kemahlı Aytekin, Çağan H Şekercioğlu, Pavel Kosintsev, Ladislav Paule, Pavel Hulva, Hans K Stenøien and 12 more

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In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Lauren M HennellySection for Evolutionary Hologenomics, Globe Institute, University of Copenhagen, Copenhagen, Denmark. lauren.hennelly@rice.edu.
Bárbara R ParreiraSection for Evolutionary Hologenomics, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
Ash NobleOrganisms and Environment, School of Biosciences, Cardiff University, Cardiff, UK.
Camilla H Scharff-OlsenSection for Evolutionary Hologenomics, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
M Çisel Kemahlı AytekinDepartment of Molecular Biology and Genetics, Koç University, Istanbul, Türkiye.
Çağan H ŞekercioğluDepartment of Molecular Biology and Genetics, Koç University, Istanbul, Türkiye.
Pavel KosintsevUral Federal University, Yekaterinburg, Russia.
Ladislav PauleTechnical University in Zvolen, Zvolen, Slovakia.ORCID http://orcid.org/0000-0002-5097-7472
Pavel HulvaDepartment of Zoology, Charles University, Prague, Czechia.ORCID http://orcid.org/0000-0002-4968-4859
Hans K StenøienNTNU University Museum, Norwegian University of Science and Technology, Trondheim, Norway.
Bilal HabibWildlife Institute of India, Dehradun, India.
Hira FatimaUniversity of Education - Attock Campus, Attock, Pakistan.
Ghulam SarwarUniversity of the Punjab, Lahore, Pakistan.
Samara P El-HaddadLebanese Wildlife, Jitta, El Metn, Lebanon.
Alexandra YoussefLebanese Wildlife, Jitta, El Metn, Lebanon.
Frank HailerOrganisms and Environment, School of Biosciences, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0002-2340-1726
Xin SunSection for Evolutionary Hologenomics, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
Nuno Filipes Gomes MartinsSection for Evolutionary Hologenomics, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
M Thomas P GilbertSection for Evolutionary Hologenomics, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-5805-7195
Benjamin N SacksMammalian Ecology and Conservation Unit, Veterinary Genetics Laboratory, Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA, USA.ORCID http://orcid.org/0000-0003-0143-6589
Mikkel-Holger S SindingDepartment of Biology, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-1371-219X
Shyam GopalakrishnanSection for Evolutionary Hologenomics, Globe Institute, University of Copenhagen, Copenhagen, Denmark.

Funding

National Science Foundation (NSF) 2208950
6 · The paper itself

Abstract

Grey wolves (Canis lupus) in Asia hold most of the species' genetic diversity and many endangered populations. However, a clear understanding of the evolutionary history of wolves in Asia is lacking, hindering their conservation. We used 98 whole genomes of wolves across Eurasia to better resolve their evolutionary history and conservation status. The strongest barriers to gene flow coincided with boundaries separating the three major wolf lineages - Indian, Tibetan, and Holarctic. Wolves in the central Asian mountain ranges belonged to the Holarctic lineage and share little ancestry with the nearby Tibetan lineage. In contrast, wolves from eastern Asia share population-wide ancestry with the Tibetan lineage, which may reflect an unsampled lineage similar to the Tibetan lineage. Wolves from southwestern Asia share population-wide ancestry with the Indian lineage, likely due to old (>6 kya) admixture events. Long-term declines and recent inbreeding have left Indian and Tibetan wolves with some of the lowest levels of genetic diversity and highest realized genetic loads. In contrast, adjacent populations have some of the highest genetic diversity, due in part to admixture along contact zones. Our study highlights southern regions of Asia as hotspots of wolf diversity and the need to conserve these remaining populations.

Indexed as

Genetic VariationGenomeWolvesAnimalsAsiaGene FlowGenetics, PopulationPhylogeny

Identifiers

PMID41444823
PMCPMC12953585

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.