ArticleSleep advances : a journal of the Sleep Research Society2025
Isolated REM sleep without atonia and isolated REM sleep behaviour disorder: a study of clinical and prognostic differences.
Article in Sleep advances : a journal of the Sleep Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Exercise Intervention for REM Sleep Behavior Disorder in Parkinson's Disease: Mechanisms and Implications for Neurorehabilitation.CNS neuroscience & therapeutics · 2026Review
- Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Study Objectives: Isolated REM sleep without atonia (iRSWA) is increasingly detected on polysomnography (PSG), yet its clinical relevance remains unclear. We compared the demographic profile, sleep physiology, comorbidities, and longitudinal outcomes of people with iRSWA and isolated REM sleep behaviour disorder (iRBD). Methods: We retrospectively reviewed PSG reports (2008-2022) from a tertiary sleep-medicine center, classifying people as iRSWA or iRBD based on self-reported dream-enactment behavior. Clinical data were extracted from charts, and PSG variables from sleep reports. Neurological and psychiatric diagnoses before the sleep examination were obtained from national registries. Comparisons used multivariable regression and Fine-Gray competing-risk models. Results: The cohort comprised 302 participants (iRSWA = 98 and iRBD = 204). Participants with iRSWA were more often female (38.8% vs 23%, Conclusions: iRSWA differs from iRBD in profile and pre-index comorbidity patterns. Our findings support the view that iRSWA may reflect mechanisms other than a uniform prodromal stage of α-synucleinopathy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.