ArticleJournal of Alzheimer's disease reports
National trends in cerebrospinal fluid biomarker testing for Alzheimer's disease in Japan.
Article in Journal of Alzheimer's disease reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Cost analyses of plasma p-tau217 versus p-tau217/Aβ42 ratio using two-step approach in the Japanese health care system.The journal of prevention of Alzheimer's disease · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Although the usefulness of cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease (AD) is well-known, their use differs widely between countries. In Japan, phospho-tau181 (p-tau181) testing for determining the cause of dementia has been covered by national health insurance since 2012 and amyloid-β (Aβ) Objective: Here, we report national trends in CSF biomarker testing for AD in Japan. Methods: We used open datasets from the national database covering nearly all health insurance claims in Japan from 2014 to 2023. Results: The annual number of health insurance claims for p-tau181 testing gradually increased from 1358 (2014) to 3420 (2023); 79-86% of claims were from inpatient settings throughout the study period. The number of claims was highest in the 75-79 age group and higher in women in older age. Regional variances were identified. The number of claims for CSF Aβ Conclusions: Although the number of health insurance claims for CSF p-tau181 testing has gradually increased, this number is low compared with the previously estimated annual diagnosis of AD. Tests are often performed in inpatient settings and regional inequity exists, whereas CSF Aβ
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