Evidence map›Paper›PMID 41445977›Full record

ReviewBioMed research international2025

The Role of miR-138 in Cardiovascular Diseases.

Taidou Jiang, Bijian Wang, Zhi Luo, Ying Xia, Yaoyu Qi, Sha Luo, Binyan Lang, Bolan Zhang, Shuzhan Zheng

Abstract readReview
In one paragraph

Review in BioMed research international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Role of miR-138 in Cardiovascular Diseases.BioMed research international · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Taidou JiangDepartment of Cardiology, The People's Hospital of Jianyang City, Jianyang, China.ORCID https://orcid.org/0009-0003-2887-4463
Bijian WangDepartment of Cardiology, Leshan People's Hospital, Leshan, China.
Zhi LuoDepartment of Cardiology, The People's Hospital of Jianyang City, Jianyang, China.
Ying XiaDepartment of Cardiology, Affiliated Hospital of Southwest Medical University, Luzhou, China, ahswmu.cn.
Yaoyu QiDepartment of Cardiology, Affiliated Hospital of Southwest Medical University, Luzhou, China, ahswmu.cn.
Sha LuoDepartment of Cardiology, Affiliated Hospital of Southwest Medical University, Luzhou, China, ahswmu.cn.
Binyan LangDepartment of Cardiology, Affiliated Hospital of Southwest Medical University, Luzhou, China, ahswmu.cn.
Bolan ZhangDepartment of Cardiology, Affiliated Hospital of Southwest Medical University, Luzhou, China, ahswmu.cn.
Shuzhan ZhengDepartment of Cardiology, Affiliated Hospital of Southwest Medical University, Luzhou, China, ahswmu.cn.ORCID https://orcid.org/0000-0002-7441-6266

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) represents the foremost cause of morbidity and mortality globally, posing a significant threat to human health. The regulatory mechanisms underlying CVD are still not fully elucidated. MicroRNA (miRNA), a class of noncoding short-chain RNA molecules, modulates individual genes or gene networks by binding to the complementary sequences of specific target genes, thereby influencing various biological processes including cell genesis, metabolism, proliferation, differentiation, and apoptosis. Among these, miR-138 plays a significant role in the onset and progression of CVDs. This article reviews the involvement of miR-138 in various cardiovascular conditions, including atherosclerosis (AS), myocardial ischemia-reperfusion injury (I/R), heart failure (HF), and pulmonary arterial hypertension (PAH), thereby offering novel insights for the prevention, diagnosis, and treatment of CVDs.

Indexed as

Cardiovascular DiseasesMicroRNAsAnimalsAtherosclerosisHumansMicroRNAsMIRN138 microRNA, humanatherosclerosiscardiovascular diseasesheart failureischemia reperfusion injurymiR-138miRNApulmonary arterial hypertension

Identifiers

PMID41445977
PMCPMC12723191

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.