Evidence map›Paper›PMID 41446084›Full record

ArticlebioRxiv : the preprint server for biology2025

A validated method for banking mixed glial cultures that yield responsive microglia.

Annalise M Sturno, James E Hassell, Katelyn M Baker, Garrett J Potter, Kimberley D Bruce

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annalise M SturnoDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America.ORCID 0009-0001-7992-7380
James E HassellDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America.ORCID 0000-0002-8336-4875
Katelyn M BakerDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America.
Garrett J PotterDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America.
Kimberley D BruceDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America.ORCID 0000-0001-5656-1534

Funding

Targeting Microglial Lipoprotein Lipase in Alzheimer's diseaseR01AG079217 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kimberley D Bruce · 2022 to 2026
$3.0M
Research Training Program in Metabolism, Obesity and Type 2 DiabetesT32DK120521 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI DANIEL Holland BESSESEN · 2020 to 2026
$2.1M
Does GLUT5-mediated Fructose Metabolism drive Microglial Dysfunction in Aging and Alzheimer's Disease?R21AG091650 · NIA · UNIVERSITY OF COLORADO DENVER · PI BRUCE, KIMBERLEY D, LANASPA GARCIA, MIGUEL ANGEL · 2024 to 2024
$442k
NIA NIH HHS R01 AG079217NIA NIH HHS R21 AG091650NIDDK NIH HHS T32 DK120521
6 · The paper itself

Abstract

Microglia, the primary immune cells of the brain, orchestrate immune responses to both external and internal stimuli in health and disease. Although several cell culture methods exist to model microglia

Indexed as

cell culturegliahigh glucoselipid dropletsLPSMicrogliaprimary cells

Identifiers

PMID41446084
PMCPMC12724494

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.