ArticleFrontiers in cellular and infection microbiology2025
Pathogen profile of co-infections and mortality determinants among patients with severe fever with thrombocytopenia syndrome.
Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical Predictors of Mortality in Severe Fever with Thrombocytopenia Syndrome: An Updated Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2026Pooled it
- Development and validation of an interpretable machine learning model for the early diagnosis of invasive pulmonary aspergillosis in patients with severe fever with thrombocytopenia syndrome: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2026Article
- Clinical outcomes and safety of tocilizumab in severe fever with thrombocytopenia syndrome: a retrospective multicenter cohort study.Frontiers in cellular and infection microbiology · 2026Article
- Secondary fungal infections in severe acute viral diseases: clinical features and underlying immune mechanisms.Frontiers in microbiology · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Severe fever with thrombocytopenia syndrome (SFTS) poses an increasing threat to global public health. This study aimed to investigate pathogen characteristics of bacterial/fungal co-infections and determine prognostic factors for mortality in co-infected SFTS patients. Methods: Demographic and clinical data were collected for eligible SFTS patients admitted to a sentinel hospital. LASSO and multivariable logistic regression were used to identify independent predictors. Results: A total of 629 SFTS patients were included, of whom 283 (45.0%) presented with co-infections. Most isolates (75.9%) obtained from respiratory specimens. Among 127 isolated fungi, Conclusion: This study highlights that bacterial/fungal co-infections are highly prevalent and clinically impactful in SFTS patients, warranting enhanced microbial surveillance and targeted intervention.
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