Evidence map›Paper›PMID 41446302›Full record

SynthesisFrontiers in psychiatry2025

Effects of mindfulness-based interventions on insight and stigma in patients with schizophrenia: a systematic review and meta-analysis.

Xiaoxin Gao, Lixiu Wu, Guolin Jin, Kunqiang Yu, Xufang Yu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoxin Gao *Seventh Ward, The Second People's Hospital of Lishui, Lishui, Zhejiang, China.
Lixiu Wu *Department of Psychiatric Rehabilitation, The Second People's Hospital of Lishui, Lishui, Zhejiang, China.
Guolin JinSeventh Ward, The Second People's Hospital of Lishui, Lishui, Zhejiang, China.
Kunqiang YuCentral Laboratory, The Second People's Hospital of Lishui, Lishui, Zhejiang, China.
Xufang YuSeventh Ward, The Second People's Hospital of Lishui, Lishui, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To systematically evaluate the impact of mindfulness-based interventions on insight and stigma in patients with schizophrenia. Methods: Randomized controlled trials (RCTs) and quasi-randomized controlled trials investigating the effects of mindfulness-based interventions on insight and stigma in schizophrenia patients were retrieved from databases including CNKI, Wanfang, VIP, CBM, PubMed, Cochrane Library, Embase, and Web of Science, with the search period spanning from inception to June 2025. Statistical analysis was performed using RevMan 5.2 software, with effect sizes expressed as standardized mean difference (SMD) and 95% confidence interval (CI). Heterogeneity was assessed using the I² statistic: a random-effects model was applied when I² ≥ 50% or P < 0.05; otherwise, a fixed-effects model was used. To evaluate the impact of study design on pooled effects, a case-deletion sensitivity analysis was conducted. Publication bias was assessed using funnel plots and Egger's test. Intervention types included mindfulness-based stress reduction, mindfulness-based cognitive therapy, group mindfulness therapy, and mindfulness-informed psychoeducation/skills training, with intervention durations ranging from 4 to 24 weeks. Results: A total of 11 RCTs and 2 quasi-randomized controlled trials involving 2,899 patients were included. The analysis revealed that the intervention group exhibited significantly better insight (SMD=1.05, 95% CI=0.67-1.43, P < 0.00001) and lower stigma (SMD=-0.81, 95% CI=-1.00 to -0.63, P < 0.00001) compared to the control group. Conclusion: Mindfulness-based interventions can significantly improve insight and reduce stigma in patients with schizophrenia, holding important clinical implications. Specifically, they may enhance treatment adherence and rehabilitation participation, decrease self-stigma, and promote the restoration of social functioning. Higher-quality, long-term follow-up randomized controlled trials (RCTs) are still needed to further validate and refine the evidence. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/, PROSPERO identifier CRD420251172478.

Indexed as

insightmeta-analysismindfulness-based interventionschizophreniastigma

Identifiers

PMID41446302
PMCPMC12722527

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.