SynthesisCurrent obesity reports2025
Obesity, Olfaction and Cognition: A Systematic Review.
Synthesis in Current obesity reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis systematic review sought to synthetize all the evidence about the relationship between olfactory function and overweight/obesity, and cognitive performance or brain structure.
methodsWe conducted a systematic review following the PRIMA methodology. PubMed and Embase were consulted up to January 2024. The articles considered eligible were those that included one group of subjects with overweight or obesity, and that performed at least one olfactory or imaging test to study olfactory function. To further understand the impact of obesity on olfaction, interventional studies focused on bariatric surgery were included.
resultsThe initial database search identified a total of 11,311 studies. Thirty studies with a total of 2482 participants were selected. Twenty-one assessed olfactory function with no intervention, among these four included cognitive assessment or brain magnetic resonance imaging (MRI). Additionally, we found nine papers that offered insight into the effect of bariatric surgery on olfaction. Fourteen of the non-interventional studies showed impaired smell capacity in individuals with high weight. Six bariatric surgery studies reported significant postoperative improvement in olfaction. Moreover, two studies measured olfactory bulb volume (OBV) and found a significant correlation between body mass index (BMI) and OBV.
conclusionsAvailable evidence suggests that there is a relationship between olfaction and overweight/obesity, which points toward olfactory impairment in this population. OBV studies remain discordant, while the findings support the idea that high BMI and hyposmia have a negative impact on cognition. However, the data are heterogeneous. Future research is needed to further understand this possible connection.
Indexed as
Identifiers
41449212What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.