Evidence map›Paper›PMID 41449232›Full record

ArticleMolecular neurobiology2025

Proteins Associated with Cognition in Amyloid-beta Positive Elders Based on Cerebrospinal Fluid Proteomics.

Min Liu, He-Ying Hu, Yan Fu, Hao-Chen Chi, Liang-Yu Huang, Lan Tan, Hao Hu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Min LiuDepartment of Neurology, Qingdao Municipal Hospital, Dalian Medical University, Qingdao, China.
He-Ying HuDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, No.5 Donghai Middle Road, Qingdao, China.
Yan FuDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, No.5 Donghai Middle Road, Qingdao, China.
Hao-Chen ChiDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, No.5 Donghai Middle Road, Qingdao, China.
Liang-Yu HuangDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, No.5 Donghai Middle Road, Qingdao, China.
Lan TanDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, No.5 Donghai Middle Road, Qingdao, China. dr.tanlan@163.com.
Hao HuDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, No.5 Donghai Middle Road, Qingdao, China. qingdaoshennei@163.com.

Funding

National Natural Science Foundation of China 82201587National Natural Science Foundation of China 82271475
6 · The paper itself

Abstract

In the pathogenesis of Alzheimer's disease (AD), amyloid-beta (Aβ) is widely recognized as a core pathological hallmark and an upstream factor contributing to cognitive decline. However, not all individuals with Aβ pathology inevitably develop cognitive impairment or progress to AD. To date, the key proteins associated with cognitive progression in Aβ-positive (A +) individuals have not been fully identified. This study aimed to identify such proteins in A + participants, defined by cerebrospinal fluid (CSF) Aβ

Indexed as

Amyloid beta-PeptidesCognitionProteomicsAgedAged, 80 and overAlzheimer DiseaseBiomarkersCognitive DysfunctionDisease ProgressionFemaleHumansMalePositron-Emission TomographyAmyloid beta-PeptidesBiomarkersAlzheimer’s diseaseAmyloid-beta positiveCognitionDementiaProteomics

Identifiers

PMID41449232

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.