Evidence map›Paper›PMID 41449443›Full record

ArticleThrombosis journal2025

Predictive value of serum homocysteine and potassium ion for short-term prognosis of patients with acute cerebral infarction following intravenous thrombolysis with recombinant tissue plasminogen activator.

Lingen Pang, Yongan Sun, Mingli He, Bingchao Xu

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Article in Thrombosis journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lingen PangDepartment of Neurology, The First Affiliated Hospital of Kangda College of Nanjing Medical University / The First People's Hospital of Lianyungang, No.182 Tongguan North Road, Lianyungang, Jiangsu, 222000, China.
Yongan SunDepartment of Neurology, The First Affiliated Hospital of Kangda College of Nanjing Medical University / The First People's Hospital of Lianyungang, No.182 Tongguan North Road, Lianyungang, Jiangsu, 222000, China.
Mingli HeDepartment of Neurology, The First Affiliated Hospital of Kangda College of Nanjing Medical University / The First People's Hospital of Lianyungang, No.182 Tongguan North Road, Lianyungang, Jiangsu, 222000, China.
Bingchao XuDepartment of Neurology, The First Affiliated Hospital of Kangda College of Nanjing Medical University / The First People's Hospital of Lianyungang, No.182 Tongguan North Road, Lianyungang, Jiangsu, 222000, China. xubc182neuro@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study evaluated the predictive value of serum homocysteine (HcY) and potassium ion (K

methodsTotally, 140 ACI patients receiving intravenous thrombolysis using rt-PA were finally included and classified into early neurological deterioration (END) and non-END groups. Serum levels of HcY and electrolytes were detected. The 90-day prognosis of patients after thrombolysis was analyzed. Influencing factors for END and poor short-term prognosis in rt-PA-treated ACI patients were identified using stepwise regression models. Correlations of serum HcY and K

resultsThe END group had higher age, atrial fibrillation, neutrophil ratio, CysC, FIB, FPG, TNF-ɑ, IL-6 and HcY levels, and National Institutes of Health Stroke Scale scores on admission but lower serum calcium ion and K

conclusionSerum HcY and K

Indexed as

Acute cerebral infarctionClinical prognosisEarly neurological deteriorationIntravenous thrombolysis with recombinant tissue-plasminogen activatorPotassium ionReceiver operating characteristic curveSerum homocysteineStepwise regression

Identifiers

PMID41449443
PMCPMC12849246

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.