SynthesisFrontiers in public health2025
Outdoor air pollutants and asthma risk in adolescents: evidence from a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- The Modern Environment and Childhood Asthma: The Role of Air Pollution and Heavy Metal Exposure.Current allergy and asthma reports · 2026Review
- Review
- 4-Hydroxynonenal, a Potential Biomarker for Lung Inflammatory Diseases.International journal of molecular sciences · 2026Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Existing epidemiological evidence linking outdoor air pollution to asthma incidence in adolescents remains inconclusive, due to methodological heterogeneity in study design, exposure assessment, and asthma case definitions. Methods: This systematic review and meta-analysis synthesized observational studies examining associations between outdoor air pollutants and adolescent asthma. Comprehensive searches of PubMed, Embase, and Scopus were conducted using Medical Subject Headings (MeSH) and free-text terms. Eligible studies reported quantitative estimates, odds ratio (OR), hazard ratio (HR), relative risk (RR), prevalence ratio (PR), incidence rate ratio (IRR), or prevalence odds ratio (POR), with corresponding 95% confidence interval (CI). Pooled estimates were calculated using inverse-variance weighted fixed- and random-effects models. Heterogeneity was assessed using Cochran's Results: Of 51 eligible studies, 40 were incorporated into the meta-analysis. Statistically significant associations were identified for each 10 μg/m Conclusion: This meta-analysis highlights significant associations between adolescent asthma and specific combustion-related air pollutants. Future research should prioritize standardized exposure metrics, life-course cohort designs, and multipollutant modeling to inform targeted prevention and public health strategies. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier PROSPERO database (CRD42024622246).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.