SynthesisFrontiers in public health2025
Prevalence and determinants of cognitive impairment in older adults with stroke in China: a systematic review.
Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Background: This systematic review aims to estimate the pooled prevalence of cognitive impairment among older adults Chinese stroke patients and to identify its demographic, clinical, and biochemical determinants, thereby providing evidence to support effective clinical prevention and intervention strategies. Methods: Eight databases (CNKI, VIP, WanFang, CBM, PubMed, Web of Science, Embase, and the Cochrane Library) were systematically searched from inception to October 24, 2024. Studies were included if they enrolled Chinese older adults stroke patients (aged ≥60 years), analyzed risk factors for cognitive impairment using case-control/cohort designs, and adopted validated cognitive assessment tools such as the Mini-Mental State Examination [MMSE], Montreal Cognitive Assessment [MoCA]). Data extraction and quality assessment (using the Newcastle-Ottawa Scale) were independently performed by two reviewers. Meta-analysis was performed using Stata version 17.0. A random-effects model was applied for high heterogeneity (I Results: A total of 46 studies, comprising 8,236 older adults stroke patients (3,281 with cognitive impairment) were included in the analysis. The pooled prevalence of cognitive impairment was 42.4% (95%CI: 36.6-48.3%), with significant heterogeneity (I Conclusion: Cognitive impairment affects 42.4% of older adults Chinese stroke patients and associated with modifiable risk factors (e.g., hypertension, diabetes) and anatomical correlates (e.g., frontal/temporal infarction). Future research should prioritize large-scale, prospective cohort studies to validate these findings and develop targeted interventions.
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