Evidence map›Paper›PMID 41450570›Full record

ArticleFrontiers in cellular and infection microbiology2025

Study on the antibacterial effect of the new anti-biofilm inhibitor ICAC on

Yubin Bai, Zixuan Shang, Rongbin Hu, Xun Gao, Zhijin Zhang, Bing Li, Zhen Zhu, Jiyu Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yubin BaiKey Laboratory of New Animal Drug Project of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development of the Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Jiangouyan, Lanzhou, China.
Zixuan ShangKey Laboratory of New Animal Drug Project of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development of the Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Jiangouyan, Lanzhou, China.
Rongbin HuKey Laboratory of New Animal Drug Project of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development of the Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Jiangouyan, Lanzhou, China.
Xun GaoKey Laboratory of New Animal Drug Project of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development of the Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Jiangouyan, Lanzhou, China.
Zhijin ZhangKey Laboratory of New Animal Drug Project of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development of the Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Jiangouyan, Lanzhou, China.
Bing LiKey Laboratory of New Animal Drug Project of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development of the Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Jiangouyan, Lanzhou, China.
Zhen ZhuSchool of Life Science and Food Engineering, Hebei University of Engineering, Handan, China.
Jiyu ZhangKey Laboratory of New Animal Drug Project of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development of the Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Jiangouyan, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rise of bacteria antibiotics resistance has bacome increasingly severe, and the development of natural compounds with antibacterial activity represents a promising approach to combat this issue. The efficacy and mechanisms of the plant-derived phenolic compound isochlorogenic acid C (ICAC) as an antibacterial and antibiofilm agent against

Indexed as

Anti-Bacterial AgentsBiofilmsEscherichia coliCyclic GMPEscherichia coli ProteinsGene Expression Regulation, BacterialMicrobial Sensitivity TestsMicroscopy, Electron, ScanningAnti-Bacterial Agentsbis(3',5')-cyclic diguanylic acidCyclic GMPEscherichia coli Proteinsbiofilmc-di-GMPEPSEscherichia colimotilityStevia rebaudiana isochlorogenic acid C

Identifiers

PMID41450570
PMCPMC12728033

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.