ArticleBMC plant biology2025
Genome-wide identification and analysis of YTH gene family and its response to MeJA and salt treatment in Panax ginseng C. A. Meyer.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Genome-Wide Characterization of theGenes · 2026Article
- Genome-Wide Analysis of YTH Domain Proteins inPlants (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
YTH domain-containing RNA-binding proteins function as m6A readers that specifically bind to m6A-modified RNAs. YTH domain-containing proteins participate in various biological processes, such as hormone signaling pathways, regulation of stress responses, RNA stability, and cellular differentiation. Despite these important roles, the characteristics and functions of YTH family genes in ginseng (Panax ginseng C. A. Meyer), a traditional medicinal herb, particularly regarding their response to MeJA (Methyl Jasmonate) treatment and salt stress on a genome-wide scale, have not yet been studied. In this study, 18 YTH genes were identified based on telomere-to-telomere reference genome of ginseng. These PgYTH genes were grouped into four subgroups by phylogenetic analysis. Moreover, the chromosomal distribution, synteny analysis, gene structures and cis-elements of PgYTH genes, and the motifs of YTH proteins were analyzed. Conserved domain analysis, multiple sequence alignment, and phase separation prediction collectively showed that PgYTH proteins exhibited typical m6A reader protein characteristics, including conserved aromatic cages (WWW/WWY) that specifically bind m6A residues, and prion-like domains (PrLDs). The PgYTH gene family showed expression differences across different growth years, tissues, and stress conditions. Among them, PgYTH12 consistently maintained the highest expression levels in ginseng roots, the main root cortex, and most cultivated varieties. PgYTH12 exhibited specific upregulation or downregulation patterns under different stresses, and showed downregulation under MeJA treatment. Correlation analysis further revealed that some PgYTH genes were significantly negatively correlated with genes involved in the ginsenoside biosynthetic pathway. qPCR results confirmed that the expression of most PgYTH genes was downregulated under MeJA treatment, whereas the expression of PgYTH8-12 was upregulated under salt stress conditions. Additionally, PgYTH12 was localized to the endoplasmic reticulum. Overall, these results lay the groundwork for future functional investigations of PgYTH genes, advancing our understanding of their role in the regulation of the ginsenoside biosynthesis pathway and stress resistance in ginseng.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.