ArticleBMC geriatrics2025
Association between triglyceride glucose index and deep vein thrombosis following total knee arthroplasty: a retrospective case-control study.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- SASP-driven vascular aging: unraveling the transcriptional nexus in endothelial senescence and cardiovascular disease.Histochemistry and cell biology · 2026Review
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10 authors.
Funding
Abstract
backgroundTotal knee arthroplasty (TKA), a frequently performed procedure for treating severe knee arthritis, is associated with notable postoperative risks, particularly deep vein thrombosis (DVT). The triglyceride-glucose (TyG) index, a marker of insulin resistance, has been linked to cardiovascular and metabolic disorders, yet its role in predicting DVT following TKA remains underexplored.
objectiveThis study aimed to assess the relationship between the TyG index and DVT incidence in patients undergoing TKA.
methodsA retrospective case-control analysis was performed on patients who underwent TKA at the First Affiliated Hospital of Soochow University from January 2020 to January 2022. The TyG index, calculated using fasting triglyceride and glucose levels, was used to categorize patients into tertiles. Multivariate logistic regression models, smooth curve fitting, and threshold effect analyses were applied to investigate the TyG-DVT relationship. The predictive capacity of TyG for DVT was further examined via receiver operating characteristic (ROC) curve analysis.
resultsHigher TyG index values were strongly linked to an elevated risk of DVT post-TKA. In the fully adjusted model, the odds ratio for the highest TyG tertile (T3) was 36.82 (95% CI: 3.24–418.16, P = 0.0036). A threshold effect emerged at a TyG index value of approximately 9.36, where DVT risk surged rapidly below this point and plateaued above it. The area under the ROC curve for TyG in predicting DVT was 0.7283, reflecting moderate predictive power.
conclusionThe TyG index shows potential as a valuable marker for identifying DVT risk in TKA patients, offering a means for early detection of high-risk individuals and enabling timely interventions to mitigate thrombotic complications.
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