ArticleJournal of diabetes investigation2026
Impact of diabetes mellitus and grip strength on postoperative outcomes in older patients undergoing cancer surgery: A single-center retrospective cohort study.
Article in Journal of diabetes investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Re: Commentary on "Impact of diabetes mellitus and grip strength on postoperative outcomes in older patients undergoing cancer surgery: A single-center retrospective cohort study".Journal of diabetes investigation · 2026Article
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Authors and funding
20 authors.
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Abstract
AIMS/
introductionDiabetes mellitus (DM) increases postoperative risks and may worsen physical function through muscle loss. Patients undergoing malignancies surgery are aging, and age-related declines in physical function, particularly sarcopenia, also adversely affects outcomes. As DM and physical decline are interrelated, we aimed to examine how they impact outcomes in older patients undergoing gastrointestinal cancer surgery. MATERIALS AND
methodsThis single-center retrospective cohort study included 1,063 older patients ≥65 years who underwent preoperative evaluation for gastrointestinal cancer between 2012 and 2019. We stratified patients based on current DM and physical function assessed by grip strength. The main outcome was postoperative survival. Cox proportional hazards models examined associated factors.
resultsAfter exclusions, 655 without DM (non-DM group) and 257 patients with DM (DM group) were analyzed (mean age: 79.1 ± 4.1 years, 66.8% male). Compared with the non-DM group, the DM group had higher body mass index (21.5 vs 22.6 kg/m
conclusionsCurrent DM did not significantly affect postoperative outcomes; however, lower grip strength was an independent risk factor for poor outcomes. The prognostic impact of reduced physical function was consistent regardless of DM status.
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