Evidence map›Paper›PMID 41458427›Full record

ArticleFrontiers in public health2025

Monitoring OTC drug sales for early detection of respiratory infectious disease outbreaks.

Junjie Li, Chen Wu, Kui Liu, Qinbao Lu, Xinyi Wang, Zheyuan Ding, Tianying Fu, Xuefeng Jiang, Haocheng Wu

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junjie LiZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Chen WuZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Kui LiuZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Qinbao LuZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Xinyi WangZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Zheyuan DingZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Tianying FuZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Xuefeng JiangPinghu Center for Disease Control and Prevention, Pinghu, China.
Haocheng WuZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In recent years, over-the-counter (OTC) drug sales have emerged as a novel indicator for symptom monitoring, attracting widespread attention in public health research globally. This study conducted weekly monitoring of five OTC drug categories related to fever respiratory system diagnostic cluster (FRSDC) - antitussive/expectorant drugs, cold medications, antibiotics, pungent and cool exterior-relieving agents, and influenza medicine - in Pinghu City, Zhejiang Province, from 2022 to 2024. Concurrently, weekly FRSDC cases from Pinghu First People's Hospital were collected. Methods: Spearman correlation analysis was used to quantify associations between OTC sales and FRSDC cases, while decision tree models evaluated the reliability of OTC data for early prediction of FRSDC trends. Results: Results showed significant positive correlations between all five OTC drugs and FRSDC cases, with synchronous seasonal peaks in winter and spring (Spearman's correlation coefficients ranged from 0.36 to 0.80, all Conclusion: These findings suggest that monitoring OTC drug sales may serve as a useful early warning indicator for FRSDC, potentially aiding public health response and resource planning.

Indexed as

CommerceDisease OutbreaksNonprescription DrugsRespiratory Tract InfectionsChinaEarly DiagnosisHumansSeasonsNonprescription Drugsearly detectionearly warningfever respiratory system diagnostic clusterOTC drug salessymptom monitoring

Identifiers

PMID41458427
PMCPMC12741107

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.