Evidence map›Paper›PMID 41458429›Full record

SynthesisFrontiers in public health2025

Systematic review and meta-analysis of oral frailty prevalence among older hospitalized patients.

Jie Gong, Liping Tan, Jing Yan, Yuying Qian, Yusu Li

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie GongDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Liping TanDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Jing YanDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yuying QianDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yusu LiDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Oral frailty, characterized by reduced oral function, represents a significant yet understudied issue among hospitalized patients, affecting treatment outcomes. Objective: To determine the prevalence of oral frailty in hospitalized patients and identify high-risk groups through stratified analyses. Methods: Nine databases, including PubMed, Web of Science, Embase, Scopus, Cochrane Library, CNKI, SinoMed, VIP, and Wanfang, were systematically searched from their inception to July 2025. Data analysis was conducted using Stata 15.0 software, employing a random-effects model to estimate overall prevalence. Subgroup analysis and meta-regression were performed to identify sources of heterogeneity. Results: This meta-analysis included 27 studies involving 11,575 hospitalized patients. The overall prevalence of oral frailty was found to be 51% (95% CI: 47-55%). Among different disease groups, patients with cancer had the highest prevalence (62, 95% CI: 57-66%), while patients with renal disease had the lowest (39, 95% CI: 32-47%). Regional analysis indicated a prevalence of 52% (95% CI: 48-56%) among patients in mainland China, and 45% (95% CI: 37-53%) in other regions. Cross-sectional studies reported a prevalence of 52% (95% CI: 48-57%), whereas cohort studies reported 42% (95% CI: 36-48%). Disease type accounted for substantial heterogeneity (I Conclusion: The findings suggest that oral frailty is highly prevalent among hospitalized patients, with prevalence varying by disease type. Therefore, establishing specific screening programs for oral frailty and integrating professional oral care into routine medical treatment are recommended to mitigate the risk of complications. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, registration no. CRD420251107503.

Indexed as

FrailtyHospitalizationOral HealthAgedAged, 80 and overChinaFemaleHumansMalePrevalencehospitalized patientsmeta-analysisoral frailtyprevalencesystematic review

Identifiers

PMID41458429
PMCPMC12738335

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.