Evidence map›Paper›PMID 41458537›Full record

Observational studyFrontiers in endocrinology2025

Bone mineral density assessment according to Italian essential assistance levels: a positive predictive value analysis based on administrative data.

Veronica Abate, Anita Vergatti, Guido Cavati, Simone Magelli, Alfonso Varriale, Daniela Merlotti, Gianpaolo De Filippo, Gaetano Piccinocchi, Lanfranco D'Elia, Luigi Gennari and 1 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Veronica Abate *Department of Clinical medicine and surgery, Federico II University, Naples, Italy.
Anita Vergatti *Department of Clinical medicine and surgery, Federico II University, Naples, Italy.
Guido CavatiDepartment of Medicine, Surgery, and Neurosciences, University of Siena, Siena, Italy.
Simone MagelliDepartment of Clinical medicine and surgery, Federico II University, Naples, Italy.
Alfonso VarrialeDepartment of Clinical medicine and surgery, Federico II University, Naples, Italy.
Daniela MerlottiDepartment of Medicine, Surgery, and Neurosciences, University of Siena, Siena, Italy.
Gianpaolo De FilippoService de Médecine Interne et Rhumatologie, Service de Santé des Armées, Hôpital National d'Instruction des Armées Percy, Clamart, France.
Gaetano Piccinocchi"COoperativa sociale di MEdici di medicina GENerale A.R.L (COMEGEN)" Medical Cooperative, Naples, Italy.
Lanfranco D'EliaDepartment of Clinical medicine and surgery, Federico II University, Naples, Italy.
Luigi Gennari *Department of Medicine, Surgery, and Neurosciences, University of Siena, Siena, Italy.
Domenico Rendina *Department of Clinical medicine and surgery, Federico II University, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Osteoporosis (OP) is the gradual loss of bone mineral density (BMD), predisposing to fragility fractures. It can be the result of aging or menopause in primary OP or other diseases and medications in secondary OP. The gold standard diagnostic tool for low BMD is represented by dual-energy X-ray absorptiometry (DXA), which has been included among the Essential Assistance Levels (EALs) in Italy for adequate prescription. This observational study based on administrative data evaluates whether the EALs are designed to predict OP (designed to include OP screening), with subsequent BMD-DXA evaluation in Italian men and women. The SIMON database was used to select women and men scheduled to undergo BMD-DXA according to EALs. Results: BMD was evaluated in 18,087 subjects [Male (M): Female (F) 889: 17198; mean age 71.3 ± 9.3 years; body mass index (BMI): 26.9 ± 4.5 Kg/m Conclusion: Italian EAL are a useful diagnostic tool for primary of OP in both sexes, with significant gender dimorphism evident in secondary OP.

Indexed as

Absorptiometry, PhotonBone DensityOsteoporosisAgedAged, 80 and overFemaleHumansItalyMaleMiddle AgedPredictive Value of Testsbone mineral densityDXAessential assistance levelsmale osteoporosisosteoporosis

Identifiers

PMID41458537
PMCPMC12740743

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.