Evidence map›Paper›PMID 41458611›Full record

SynthesisFrontiers in oncology2025

Comparative efficacy of various physical therapies on pain, fatigue, quality of life and functional impairment in breast cancer survivors: a network meta-analysis of randomized controlled trials.

Yuan Luo, Qi Huang, Xiao Chen, Hongju Peng, Yu Li, Li Chen, Liyue Zhang, Yi Huang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuan LuoThe First People's Hospital of Neijiang City, Sichuan, Neijiang, China.
Qi HuangThe First People's Hospital of Neijiang City, Sichuan, Neijiang, China.
Xiao ChenThe First People's Hospital of Neijiang City, Sichuan, Neijiang, China.
Hongju PengThe Second People's Hospital of Neijiang City, Sichuan, Neijiang, China.
Yu LiThe First People's Hospital of Neijiang City, Sichuan, Neijiang, China.
Li ChenThe First People's Hospital of Neijiang City, Sichuan, Neijiang, China.
Liyue ZhangThe First People's Hospital of Neijiang City, Sichuan, Neijiang, China.
Yi HuangThe Second People's Hospital of Neijiang City, Sichuan, Neijiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to conduct a comparative analysis of the effects of different physical therapies on the pain, fatigue, functional impairment, quality of life, and grip strength of breast cancer survivors. Design:A systematic review and network meta-analysis were conducted. Methods: The process of screening, data extraction, coding and bias risk assessment is conducted in an independent and duplicated manner. The primary outcome measures are subjected to evaluation through the utilization of Bayesian network meta-analysis. The online Meta-analysis Confidence (CINeMA) tool is employed to assess the quality of evidence. The data source: PubMed, Cochrane Library, Web of Science and Embase. Eligibility criteria for selecting studies: This article examines any randomized controlled trials that involve physical therapy for breast cancer survivors. Results: A total of 111 RCTs involving 6888 participants and 16 types of physical therapy interventions were included. A network meta-analysis showed that all physical therapy measures had some effect on breast cancer survivors compared with placebo. Virtual reality technology may be more effective in relieving pain, electrotherapy may be more effective in restoring functional disorders, kinesiology taping may be more effective in terms of fatigue, quality of life (physical aspect), and grip strength, and aerobic exercise may be more effective in relieving Quality of life (Mental Component). The final curvature under the cumulative sequence curve indicates that virtual reality technology, intramuscular adhesives, and mixed exercises are relatively good auxiliary treatment methods. The degree of confidence varies from high to very low according to CINeMA. Conclusion: For breast cancer survivors, mental improvements are just as important as physical improvements. Researchers should pay more attention to the overall benefits and the safety and feasibility of trials. However, this conclusion still needs to be further verified by a large number of multi-center and large sample size RCT.

Indexed as

aerobic exercisebreast cancermanual lymphatic therapynetwork meta-analysisphysical therapy

Identifiers

PMID41458611
PMCPMC12740869

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.