Evidence mapPaperPMID 41458752Full record

ArticleCureus2025

A Case of Trousseau Syndrome: A Report Detailing Recurrent Ischaemic Strokes Associated With Metastatic Pancreatic Cancer and Pulmonary Embolisms Despite Treatment With Direct Oral Anticoagulation.

Ei Thinzar Aung, Morgan W Hayden, Karen Chouhan, Ye Thurein Mon, Laura Skeldon

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ei Thinzar AungStroke Medicine, The Grange University Hospital, Newport, GBR.
Morgan W HaydenInternal Medicine, The Grange University Hospital, Newport, GBR.
Karen ChouhanStroke Medicine, The Grange University Hospital, Newport, GBR.
Ye Thurein MonGeriatrics, The Grange University Hospital, Newport, GBR.
Laura SkeldonStroke Medicine, The Grange University Hospital, Newport, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is a malignancy strongly associated with cancer-related hypercoagulability. Venous thromboses are a well-documented complication of pancreatic cancer, but there is less awareness and focus on arterial events such as ischaemic stroke and myocardial infarction. We present the case of a patient who was diagnosed with ischaemic stroke preceding a diagnosis of an occult metastatic pancreatic malignancy and concurrent pulmonary embolism. Despite treatment with therapeutic doses of direct oral anticoagulation, the patient subsequently developed recurrent bilateral ischaemic strokes. This case highlights the challenges of managing mixed venous and arterial thromboembolic disease in patients with pancreatic cancer and illustrates the aggressive, refractory nature of Trousseau syndrome.

Indexed as

anticoagulationdirect oral anticoagulant therapyhypercoaguable statehypercoagulable statepancreatic capulmonary embolism (pe)recurrent ischemic strokestroketrousseau’s syndrome

Identifiers

PMID41458752
PMCPMC12738081

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.