ReviewCureus2025
Radiological Innovations for Monitoring Bone Regeneration and Fracture Healing.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Neuroimmune regulation of post-traumatic bone regeneration: focus on inflammatory switching and functional recovery.Frontiers in immunology · 2026Review
- Characterizing MicroPure ultrasound detectability of mineralization-related echogenic foci in regenerate bone during tibial bone transport.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate monitoring of bone regeneration and fracture healing is essential for optimizing orthopedic outcomes and guiding timely clinical interventions. While radiography, computed tomography (CT), and magnetic resonance imaging (MRI) remain standard tools, their limitations, particularly in detecting early biological activity and evaluating healing around implants, have prompted exploration of advanced imaging techniques. This narrative review was conducted through a structured search of PubMed, Scopus, and Web of Science databases for studies published between 2000 and 2025 using predefined keywords related to bone healing and imaging. Peer-reviewed original studies, systematic reviews, and clinically relevant preclinical research focusing on radiological assessment of fracture healing were included, while non-English articles, conference abstracts, and non-peer-reviewed sources were excluded. Study quality and potential sources of bias were appraised based on clarity of methodology, imaging reproducibility, and applicability to clinical practice. Recent innovations, such as high-resolution and functional MRI, quantitative CT (qCT), hybrid positron emission tomography (PET) imaging, and advanced ultrasound modalities, provide deeper insights into trabecular microarchitecture, perfusion, and osteoblastic activity. Metabolic PET tracers, radiomics, artificial intelligence (AI), and 3D printing further enhance diagnostic precision and support personalized treatment planning. Despite their promise, these modalities face challenges including high cost, limited accessibility, lack of standardization, and the need for robust clinical validation. This review summarizes the current radiological landscape, highlights emerging opportunities, and outlines future steps required for integrating advanced imaging tools into routine orthopedic practice.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.