Evidence map›Paper›PMID 41459236›Full record

ArticleFrontiers in microbiology2025

Dietary resveratrol modulates rumen microbiota and metabolic function in Tibetan sheep: an integrated 16S rRNA sequencing and metabolomics analysis.

Wenling Xie, Yu Zhang, Yuan Feng, Yujie Li, Linsheng Gui, Shengzhen Hou, Lijuan Han, Zhenzhen Yuan, Chao Yang, Shengnan Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
  2. Effects of Replacing Alfalfa withAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenling XieCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai, China.
Yu ZhangCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai, China.
Yuan FengDepartment of Pharmacy, College of Medicine, Qinghai University, Xining, China.
Yujie LiDepartment of Pharmacy, College of Medicine, Qinghai University, Xining, China.
Linsheng GuiCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai, China.
Shengzhen HouCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai, China.
Lijuan HanCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai, China.
Zhenzhen YuanCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai, China.
Chao YangState Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, China.
Shengnan SunCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Resveratrol (RES), a natural plant polyphenolic compound, can be used as a dietary supplement and has shown good application after addition to monogastric animal diets, but fewer studies have been conducted in ruminants, especially in Tibetan sheep where no deeper studies have been made. In this study, we used 16S rRNA and metabolomics systems to investigate the effects of different doses of resveratrol added to the diets of Tibetan sheep on the microbial community structure and metabolomics of their rumen. Results: The results showed a significant ( Conclusion: In summary, daily supplementation with 1.5 g of resveratrol (H-RES) improved rumen morphology and fermentation processes in Tibetan sheep. These improvements were closely related to changes in microbial community structure and metabolite interactions. The study of rumen microbial community structure and metabolite changes provides new ideas for regulating the rumen environment of Tibetan sheep.

Indexed as

16S rRNAmetabolitesmicrobiotaresveratrolrumen developmentTibetan sheep

Identifiers

PMID41459236
PMCPMC12742471

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.