Evidence map›Paper›PMID 41459405›Full record

ArticleSleep medicine research2025

Obstructive Sleep Apnea and Aging: A Narrative Review.

David Brower, Eric Pan, William Goss, Younghoon Kwon, William Healy

Abstract read
In one paragraph

Article in Sleep medicine research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David BrowerWellstar Medical College of Georgia, Division of Pulmonary, Critical Care, and Sleep Medicine, Augusta, GA.
Eric PanWellstar Medical College of Georgia, Division of Pulmonary, Critical Care, and Sleep Medicine, Augusta, GA.
William GossWellstar Medical College of Georgia, Division of Pulmonary, Critical Care, and Sleep Medicine, Augusta, GA.
Younghoon KwonUniversity of Washington, Division of Cardiology, Seattle, WA.
William HealyWellstar Medical College of Georgia, Division of Pulmonary, Critical Care, and Sleep Medicine, Augusta, GA.

Funding

Sleep Apnea-Specific Nocturnal Blood Pressure Surge to Determine Cardiovascular Risks and Therapeutic Benefits in Patients with Obstructive Sleep ApneaR01HL158765 · NHLBI · UNIVERSITY OF WASHINGTON · PI KWON, YOUNGHOON · 2021 to 2025
$3.5M
Photoplethysmography Analysis to Assess Cardio-Cerebrovascular Impact of SleepR21AG070576 · NIA · UNIVERSITY OF WASHINGTON · PI KWON, YOUNGHOON · 2020 to 2021
$530k
Cardiovascular implications of sleep characteristics using real-world objective sleep dataR21HL150502 · NHLBI · UNIVERSITY OF WASHINGTON · PI KWON, YOUNGHOON, SOHN, MIN-WOONG · 2020 to 2021
$261k
Deep learning of awake and sleep electrocardiography to identify atrial fibrillation risk in sleep apneaR21HL167126 · NHLBI · UNIVERSITY OF WASHINGTON · PI AKBILGIC, OGUZ, AZARBARZIN, ALI · 2023 to 2024
$202k
NHLBI NIH HHS R01 HL158765NHLBI NIH HHS R21 HL150502NHLBI NIH HHS R21 HL167126NIA NIH HHS R21 AG070576
6 · The paper itself

Abstract

Obstructive sleep apnea is one of the most common sleep disorders. It can greatly increase patient sleepiness, and is associated with cardiovascular and neurological disease. As people age, they are more likely to develop the disease, so with an aging population, understanding how OSA effects the elderly is increasingly important. This review summarizes sleep medicine's understanding of the disease in older people. It discusses the epidemiology of OSA in this population and then examines differences in risk factors relevant in the elderly, including the effects of menopause. Next, we review the symptomology, with special attention paid to comorbid insomnia, before examining challenges in diagnosing OSA in older people. We examine the pathophysiology of OSA in the elderly with particular focus on changes in anatomy and sleep architecture, as well as positional OSA. We then discuss the intricacies and effectiveness of various treatments including continuous positive airway pressure and surgically implanted devices. We finish by exploring OSA's implications in cognitive decline and Alzheimer's disease. OSA is a very common disease in the elderly, with the potential to significantly reduce the patient's quality of life. This review should serve as a resource for sleep medicine physicians to further educate themselves on this topic.

Indexed as

AgingContinuous Positive Airway PressureObstructive Sleep Apnea

Identifiers

PMID41459405
PMCPMC12742971

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.