Evidence mapPaperPMID 41459628Full record

ReviewCancer medicine2026

Exploring the Role of Long Noncoding RNAs in Breast Cancer Progression: A Comprehensive Study on Biomarkers and Therapeutic Approaches.

Ramin Moeini, Amin AhsanAlkhat, Saeid Ghorbian

Abstract readReview
In one paragraph

Review in Cancer medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ramin MoeiniDepartment of Biology, Ta.C., Islamic Azad University, Tabriz, Iran.
Amin AhsanAlkhatDepartment of Biology, Ta.C., Islamic Azad University, Tabriz, Iran.
Saeid GhorbianDepartment of Biology, Ta.C., Islamic Azad University, Tabriz, Iran.ORCID https://orcid.org/0000-0003-0780-3159

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmong the many forms of cancer that plague women all over the globe, breast cancer (BC) is one of the most prevalent kinds. BC is a multifaceted disease that can manifest in many ways depending on the individual.

aimsThe identification of new biomarkers that may be used to diagnose and prognosis of the BC, as well as those that can aid in the creation of novel therapeutic approaches and the understanding of how to regulate multiple pathways in metastasis, may initiate the process of creating novel therapeutic interventions for cancer patients. MATERIALS AND

methodsAccording to data from recent studies, long noncoding RNAs (LncRNAs) contribute to the development of BC via several distinct biochemical mechanisms. Remembering that long LncRNAs are longer than 200 nucleotides and do not encode proteins is essential.

resultsThrough its interaction with the EGF, TGF-β, NF-κB, PI3K/AKT, and p53 pathways, the abnormal production of LncRNA has a substantial impact on the progression of BC.

conclusionsThis research investigates the biological properties of LncRNAs to ascertain their role in regulating cell signaling pathways and the subsequent changes in cell survival, invasion, and proliferation components that characterize BC.

Indexed as

Biomarkers, TumorBreast NeoplasmsRNA, Long NoncodingCell ProliferationDisease ProgressionFemaleGene Expression Regulation, NeoplasticHumansPrognosisSignal TransductionBiomarkers, TumorRNA, Long Noncodingbreast cancerLncRNAmetastasisoncogeneprognosistumor suppressor

Identifiers

PMID41459628
PMCPMC12746216

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.