Evidence map›Paper›PMID 41461027›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Detoxification of conifer antimicrobial defenses promotes entomopathogenic fungus infection of bark beetles.

Ruo Sun, Baoyu Hu, Yoko Nakamura, Michael Reichelt, Xingcong Jiang, Katrin Luck, Christian Paetz, Jonathan Gershenzon

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Detoxification of conifer antimicrobial defenses promotes entomopathogenic fungus infection of bark beetles.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruo SunDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0001-9861-6097
Baoyu HuDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.
Yoko NakamuraDepartment of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0002-9622-1005
Michael ReicheltDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0002-6691-6500
Xingcong JiangDepartment of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.
Katrin LuckDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0009-0007-1377-8523
Christian PaetzResearch Group Biosynthesis/NMR, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0002-5776-7574
Jonathan GershenzonDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0002-1812-1551

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After consumption by herbivores, plant antimicrobial defense compounds may enhance herbivore immunity to pathogenic microbes. In conifer-bark beetle interactions, beetles ingest large quantities of phloem tissue containing high concentrations of antimicrobial phenolic glucosides, such as stilbenes and flavonoids. It is not known, however, if these compounds increase bark beetle resistance to pathogens. We showed that Eurasian spruce bark beetles (

Indexed as

BeauveriaColeopteraPiceaAnimalsGlucosidesHerbivoryPhloemPlant DiseasesGlucosidesdetoxificationentomopathogenic fungusphenolic metabolismplant–insect–microbe interactionsplant secondary metabolite

Identifiers

PMID41461027
PMCPMC12773783

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.