Evidence map›Paper›PMID 41461647›Full record

SynthesisNPJ primary care respiratory medicine2025

Comparative efficacy of pulmonary rehabilitation delivery models on dyspnoea, exercise capacity and health-related quality of life in chronic respiratory disease: a systematic review and network meta-analysis.

Jia Song, Qin Wang, Chongyang Zhao, Lei Wang, Li Li, Deying Kang

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in NPJ primary care respiratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jia Song *Department of Evidence-based Medicine and Clinical Epidemiology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Qin Wang *Department of Evidence-based Medicine and Clinical Epidemiology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Chongyang ZhaoDepartment of Evidence-based Medicine and Clinical Epidemiology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Lei WangDivision of Internal Medicine, Institute of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, China.
Li LiChengdu Fifth People's Hospital, Chengdu, China.
Deying KangDepartment of Evidence-based Medicine and Clinical Epidemiology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China. deyingkang@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review aimed to systematise the different models used to deliver pulmonary rehabilitation (PR) during chronic respiratory diseases (CRDs) and explore which ones are the most effective in terms of dyspnea, exercise capacity, and health-related quality of life (HRQoL). The literature search strategy involved structured searches of PubMed, Web of Science, and Cochrane Library for relevant articles published from January 2013 to March 2025. The risk of bias was assessed using ROB 2.0. Descriptive analysis and meta-analysis were performed. Forest plots and the node-splitting model presented results. Network meta-analysis was conducted in R 4.3.2. 33 studies(n = 2538) were included in this review and of those, 27 studies(n = 2106) were used for meta-analysis. 22 (66.7%) studies were at high risk of bias and the certainty of evidence for all outcomes (6MWT, dyspnea, HRQoL) was rated as low due to study limitations and imprecision. Compared with usual care, PR patients have significant improvement on 6MWT as well as mMRC (both P < 0.01). The cumulative ranking probability curves and forest plot analyses revealed a hierarchical efficacy profile among rehabilitation modalities for CRDs, with outpatient presented the larger effects on mMRC (mean difference (MD)= -0.82, 95%Cl [-1.45, -0.19]), 6MWT(MD = 65.45, 95%Cl [45.06, 85.84]). Our findings suggest that PR probably improves exercise capacity and reduces dyspnea in patients with CRDs, with outpatient-based programmes generally showing the largest effects, while the high risk of bias limits interpretation of this finding.PROSPERO ID: CRD420251013615.

Indexed as

DyspneaExercise TolerancePulmonary Disease, Chronic ObstructiveQuality of LifeChronic DiseaseHumansNetwork Meta-Analysis as Topic

Identifiers

PMID41461647
PMCPMC12852677

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.