Trial reportScientific reports2025
Effect of therapeutic lifestyle change on metabolic syndrome in adults: a randomized controlled trial.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic syndrome (MetS) is the co-occurrence of multiple cardio-metabolic risk factors, including central obesity, hyperglycemia, hypertension, and dyslipidemia. MetS doubles the risk of CVD and increases the risk of T2DM fivefold. Therapeutic lifestyle change (TLC) has been recommended as the primary intervention for MetS. This interventional study was aimed at assessing the effect of TLC on MetS and other metabolic components. A two-arm, double-blinded community-based RCT was used among MetS-positive adults. Participants were randomly assigned to either the intervention group (IG) (n = 75) or the control group (CG) (n = 75). Participants in the IG received a TLC program focused on dietary modification, exercise, and behavioral change. A booklet and biweekly counseling were given, containing comprehensive information on MetS and its management approach. The intervention was implemented for three months. Baseline and end line data were collected. ANCOVA and GEE tests were used for continuous and categorical outcome variables, respectively. TLC improved almost all of the metabolic risk factors simultaneously, including weight, WC, BMI, TC, FBG, TG, and SBP. On average over time, the IG has - 868 g, -1.65 cm, -0.36 kg/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.