Evidence map›Paper›PMID 41462007›Full record

ArticleJournal of fluorescence2026

Computational Investigation of Dicyanoisophorone-Based Fluorophores: Substituent and Site Effects.

Yating Ding, Zhengze Zhang, Rui Wu, Ying Xu, Qu Zhang, Zhao Liu, Junqiang Lei

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yating Ding *The first Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Zhengze Zhang *State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China.
Rui WuThe first Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Ying XuThe first Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Qu ZhangThe first Clinical Medical College of Lanzhou University, Lanzhou, 730000, China.
Zhao LiuThe first Clinical Medical College of Lanzhou University, Lanzhou, 730000, China. docliuzhao08@163.com.
Junqiang LeiThe first Clinical Medical College of Lanzhou University, Lanzhou, 730000, China. leijq2011@126.com.

Funding

National Natural Science Foundation of China 81960323
6 · The paper itself

Abstract

Dicyanoisophorone-based fluorophores (DF) hold broad application prospects in the fields of fluorescent probes and biomedicine. However, the structure-activity relationship (SAR) of these fluorophores following the introduction of different substituents at distinct sites remains unclear, which limits their further application and performance optimization. In this study, we systematically investigated the effects of introducing electron-donating groups (Me, OMe, NH₂, NMe₂ and NPh₂) and electron-withdrawing groups (F, NO₂, COOH, CN and SO₃H) at the C3, C4, and C6 sites of the benzene ring on the structure and properties of DF from a theoretical perspective, thereby providing a theoretical basis and reference for the subsequent modification and improvement of this class of fluorescent probes.

Indexed as

DCI-based fluorescenceSubstituent and site effectsTD-DFTTheoretical spectral calculation

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.