Evidence map›Paper›PMID 41462601›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Hyperoside Promotes Mitochondrial Autophagy Through the miR-361-5p/PI3K/Akt/mTOR Signaling Pathway, Thereby Improving UVB-Induced Photoaging.

Danni Yang, Jiayi Le, Shuyun Xiao, Yulin Cui, Wanfang Zhu, Kouharu Otsuki, Wei Li, Jian Xu, Feng Feng, Jie Zhang

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Danni YangSchool of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Jiayi LeSchool of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Shuyun XiaoSchool of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Yulin CuiSchool of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Wanfang ZhuCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130022, China.
Kouharu OtsukiFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi 274-8510, Chiba, Japan.ORCID 0000-0001-6730-0663
Wei LiFaculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi 274-8510, Chiba, Japan.ORCID 0000-0003-4143-8597
Jian XuSchool of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Feng FengSchool of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Jie ZhangSchool of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.

Funding

Fundamental Research Funds for the Central Universities 2632025XCZX02
6 · The paper itself

Abstract

Ultraviolet radiation B (UVB) radiation can induce oxidative stress, DNA damage, and inflammation, leading to skin wrinkling, impaired barrier function, and an increased risk of cancer. Addressing or preventing photoaging may provide a promising therapeutic avenue for these conditions. Hyperoside (HY), a compound abundantly found in medicinal plants including

Indexed as

hyperosidemiRNAmitophagyphotoagingPI3K/Akt/mTOR

Identifiers

PMID41462601
PMCPMC12729947

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.