Evidence mapPaperPMID 41462804Full record

ReviewChildren (Basel, Switzerland)2025

Dietary Fat and Protein Intake and Their Impact on Glycemic Control in Pediatric Type 1 Diabetes: A Narrative Review.

Kosmas Margaritis, Vasiliki Rengina Tsinopoulou, Eleni P Kotanidou, Assimina Galli-Tsinopoulou

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kosmas MargaritisUnit of Pediatric Endocrinology, Diabetes and Metabolism-Collaborative Sweet Center, 2nd Department of Paediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, AHEPA University General Hospital, Stilponos Kyriakidi 1, 54636 Thessaloniki, Greece.ORCID 0000-0002-6337-2499
Vasiliki Rengina TsinopoulouUnit of Pediatric Endocrinology, Diabetes and Metabolism-Collaborative Sweet Center, 2nd Department of Paediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, AHEPA University General Hospital, Stilponos Kyriakidi 1, 54636 Thessaloniki, Greece.ORCID 0000-0002-2531-2313
Eleni P KotanidouUnit of Pediatric Endocrinology, Diabetes and Metabolism-Collaborative Sweet Center, 2nd Department of Paediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, AHEPA University General Hospital, Stilponos Kyriakidi 1, 54636 Thessaloniki, Greece.ORCID 0000-0002-8292-4471
Assimina Galli-TsinopoulouUnit of Pediatric Endocrinology, Diabetes and Metabolism-Collaborative Sweet Center, 2nd Department of Paediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, AHEPA University General Hospital, Stilponos Kyriakidi 1, 54636 Thessaloniki, Greece.ORCID 0000-0002-8503-3893

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbohydrates have been the center of type 1 diabetes dietary management. Emerging evidence highlights the important effects of fat and protein in postprandial hyperglycemia, suggesting that an increase in daily fat and protein intake, combined with appropriate insulin dose adjustments, might lead to better glycemic control. It is well studied that meals containing fat or protein lead to late postprandial hyperglycemia. Studies that researched the use of these macronutrients observed the need for extended or dual wave boluses to achieve euglycemia and that no consistent improvement in HbA1c or time in range was related to higher protein or fat intake. Optimizing glycemic control in pediatric T1D requires strategies beyond carbohydrate counting. While balanced macronutrient distribution remains the main solid factor in stable glycemic profiles, more studies regarding the variety of macronutrients' formulation in optimizing glycemic control are needed.

Indexed as

adolescentschildrenfatglycemic controlinsulin dosingmacronutrientsproteintype 1 diabetes

Identifiers

PMID41462804
PMCPMC12731740

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.