Evidence mapPaperPMID 41463004Full record

ArticleBiomedicines2025

MAPK Pathway Activation Patterns in the Synovium Reveal ERK1/2 and EGFR as Key Players in Osteoarthritis.

Ivana Jurić, Petar Todorović, Nela Kelam, Danica Boban, Patricija Bajt, Anita Racetin, Matko Rošin, Davor Čarić, Katarina Vukojević

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ivana JurićDepartment of Emergency Medicine, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Petar TodorovićDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2A, 21000 Split, Croatia.ORCID 0009-0005-6953-0135
Nela KelamDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2A, 21000 Split, Croatia.ORCID 0000-0002-6529-5474
Danica BobanDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2A, 21000 Split, Croatia.ORCID 0000-0002-4600-3149
Patricija BajtDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2A, 21000 Split, Croatia.
Anita RacetinDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2A, 21000 Split, Croatia.
Matko RošinDepartment of Surgery, Orthopaedics and Traumatology Division, University Hospital of Split, Spinčićeva 1, 21000 Split, Croatia.
Davor ČarićDepartment of Surgery, Orthopaedics and Traumatology Division, University Hospital of Split, Spinčićeva 1, 21000 Split, Croatia.
Katarina VukojevićDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2A, 21000 Split, Croatia.ORCID 0000-0003-2182-2890

Funding

Croatian Science Foundation IP-2022-10-8720
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EGFRERK 1/2JNKMAPKosteoarthritisp38synovial membrane

Identifiers

PMID41463004
PMCPMC12730786

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.