Evidence mapPaperPMID 41463281Full record

ReviewCancers2025

Silent Players, Loud Impact: The Influence of lncRNAs on Melanoma Progression.

Kajetan Kiełbowski, Maciej Ćmil, Aleksandra Dach, Aleksandra Cole, Oliwia Jerzyńska, Estera Bakinowska, Paulina Plewa, Andrzej Pawlik

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kajetan KiełbowskiDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-8227-6753
Maciej ĆmilDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0009-0000-1594-5646
Aleksandra DachDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0009-0009-8798-5415
Aleksandra ColeDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0009-0006-2902-5975
Oliwia JerzyńskaDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Estera BakinowskaDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Paulina PlewaDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0009-0008-6821-0086
Andrzej PawlikDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-6557-1208

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNA (ncRNA) encompasses a large family of molecules that are crucial regulators of gene expression. This family includes microRNA, piwi-interacting RNA, and long non-coding RNA (lncRNA); each class is associated with different mechanisms of action that influence gene expression. Based on the available evidence, these molecules have important roles in physiological and pathological processes. For example, ncRNAs are strongly implicated in oncogenesis by mediating the expression of tumour suppressors and oncogenes. This review comprehensively describes the latest findings regarding the roles of lncRNAs in the pathophysiology of melanoma. Key aspects of melanoma biology and various mechanisms regulated by lncRNAs are discussed. Furthermore, future areas exploring potential biomarkers and therapeutic targets are presented.

Indexed as

long non-coding RNAmelanomaoncologypost-transcriptional regulationtranscription

Identifiers

PMID41463281
PMCPMC12731060

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.