Evidence map›Paper›PMID 41463330›Full record

ReviewBiomolecules2025

Herbal Medicines in the Management of Diabetes Mellitus: Plants, Bioactive Compounds, and Mechanisms of Action.

Jamil Atef Chahrour, Zaher Abdel Baki, Dalia El Badan, Ghassan Nasser, Marc Maresca, Akram Hijazi

Abstract readReview
In one paragraph

Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Ethnobotany, Phytochemistry, and Pharmacological Activities ofInternational journal of molecular sciences · 2026
    Pooled it
  2. Antidiabetic Properties ofLife (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Article
  5. Rambutan (Molecules (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jamil Atef ChahrourDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, P.O. Box 115020, Beirut 1107-2809, Lebanon.ORCID 0009-0000-4916-8873
Zaher Abdel BakiCollege of Engineering and Technology, American University of the Middle East, Egaila 54200, Kuwait.ORCID 0000-0002-2070-5855
Dalia El BadanDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, P.O. Box 115020, Beirut 1107-2809, Lebanon.ORCID 0000-0002-1043-6954
Ghassan NasserDoctoral School of Science and Technology, Research Platform for Environmental Science (PRASE), Lebanese University, P.O. Box 115020, Beirut 1107-2809, Lebanon.ORCID 0000-0003-3913-8544
Marc MarescaAix Marseille Univ, CNRS, Centrale Marseille, iSM2, 13013 Marseille, France.ORCID 0000-0002-3585-4765
Akram HijaziDoctoral School of Science and Technology, Research Platform for Environmental Science (PRASE), Lebanese University, P.O. Box 115020, Beirut 1107-2809, Lebanon.ORCID 0000-0003-4984-8531

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, herbal medicines (HMs) have been gaining significant attention as alternative or complementary therapeutic options. This is because synthetic drugs are expensive and have side effects, but also because herbal medicines have a rich content of effective bioactive compounds. These natural agents have been widely investigated for their potential in the prevention and management of chronic diseases including cardiovascular disorders, infections, metabolic disorders, neurological disorders, inflammatory disorders digestive diseases, oxidative stress-related diseases, and diabetes mellitus. In this review, we highlight the roles and impacts of various medicinal plants originating from diverse families, showing their bioactive characteristics, and the mechanisms through which they exert antidiabetic effects by regulating insulin secretion, oxidative stress, glucose uptake, and inflammatory pathways. In contrast to previous reviews, our study highlights the role of plants that are less explored, and integrates recent findings as well as future directions and biotechnological applications in plant-based management of diabetes.

Indexed as

Diabetes MellitusHerbal MedicineHypoglycemic AgentsPhytochemicalsPlants, MedicinalAnimalsHumansOxidative StressHypoglycemic AgentsPhytochemicalsantidiabetic effectsdiabetes mellitusglucose transporter type 4 (GLUT4)herbal-based medicinehyperglycemiamedicinal plantsphytochemicals

Identifiers

PMID41463330
PMCPMC12731053

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.