Evidence map›Paper›PMID 41463657›Full record

ArticleBioengineering (Basel, Switzerland)2025

Ultra-Weak Photon Emission Demonstrates Specificity for Anxiety over Pain in Cannabis-Treated Chronic Neuropathic Pain: A Biomarker Validation Study.

Mustafa Yassin, Dror Robinson, Muhammad Khatib, Hamza Murad, Feras Qawasme, Eitan Lavon

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mustafa YassinDepartment of Orthopedics, Hasharon Hospital, Rabin Medical Center, Affiliated to Tel Aviv University, Petah Tikwa 4937211, Israel.ORCID 0000-0001-8260-6492
Dror RobinsonDepartment of Orthopedics, Hasharon Hospital, Rabin Medical Center, Affiliated to Tel Aviv University, Petah Tikwa 4937211, Israel.ORCID 0000-0003-2517-4069
Muhammad KhatibDepartment of Orthopedics, Hasharon Hospital, Rabin Medical Center, Affiliated to Tel Aviv University, Petah Tikwa 4937211, Israel.
Hamza MuradDepartment of Orthopedics, Hasharon Hospital, Rabin Medical Center, Affiliated to Tel Aviv University, Petah Tikwa 4937211, Israel.
Feras QawasmeDepartment of Orthopedics, Hasharon Hospital, Rabin Medical Center, Affiliated to Tel Aviv University, Petah Tikwa 4937211, Israel.
Eitan LavonManagement Department, Hasharon Hospital, Rabin Medical Center and Clalit Health Services, Tel Aviv 6139001, Israel.ORCID 0009-0005-7630-5155

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pain management increasingly seeks objective biomarkers to complement subjective assessments. Ultra-weak photon emission (UPE), measurable via gas discharge visualization (GDV), has been proposed as a potential biomarker for various health conditions. However, the specificity of UPE measurements for pain versus comorbid conditions remains unexplored. This prospective cohort study followed 200 adults with electrodiagnostically confirmed neuropathic pain receiving cannabis therapy for 48 months. Assessments included the Numerical Rating Scale (NRS) for pain, Generalized Anxiety Disorder-7 (GAD-7) for anxiety, and Biowell UPE measurements. Cannabis therapy yielded 91.5% clinical response rate. However, UPE measurements showed striking differential validity: Biowell stress correlated strongly with GAD-7 (r = 0.579,

Indexed as

anxietybiomarker specificitybiophotonschronic paindifferential validitygas discharge visualizationmedical cannabisoxidative stress

Identifiers

PMID41463657
PMCPMC12729612

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.