Distinct Effects of GnRH Immunocastration Versus Surgical Castration on Gut Microbiota.

Fanli Kong, Ruohan Yang, Xingyu Zhou, Yuanyuan Shen, Wenhao Wei, Xianyin Zeng, Xiaogang Du, Xinfa Han

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fanli KongCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.ORCID 0000-0001-8406-7621

Ruohan YangCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.

Xingyu ZhouLivestock and Poultry Multi-Omics Key Laboratory of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.

Yuanyuan ShenLivestock and Poultry Multi-Omics Key Laboratory of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.

Wenhao WeiCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.

Xianyin ZengCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.

Xiaogang DuCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.

Xinfa HanCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.

Funding

National Key R & D Program of China 2023YFD1300400, 2022YFF1000100, and 2022YFD1301200National/Provincial Undergraduate Training Program on Innovation and Entrepreneurship 202510626001Sichuan Science and Technology Program 2021ZDZX0008 and 2021YFYZ0030the China Postdoctoral Science Foundation 2023M732512the National Natural Science Foundation of China 32202630)the Science and Technology Projects of Xizang Autonomous Region of China XZ202501ZY0147

6 · The paper itself

Abstract

Surgical castration, a common practice in animal husbandry, raises animal welfare concerns and adversely affects growth performance. Active immunization against gonadotropin-releasing hormone (GnRH) provides a non-surgical alternative. Both methods ultimately suppress sex hormone production, but their comparative effects on the gut microbiota, a crucial regulator of host health and metabolism, remain unclear. Here, 60 Sprague Dawley (SD) rats were randomly allocated into three groups-control (

Indexed as

GnRH immunocastrationgut microbiotaSD ratssexual dimorphismsurgical castration

Identifiers

PMID41463797

DOI10.3390/ani15243512

PMCPMC12730046

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.