Evidence mapPaperPMID 41465121Full record

ReviewGenes2025

The Utility of Genome-Wide Association Studies in Inherited Arrhythmias and Cardiomyopathies.

Saif Dababneh, Arya Ardehali, Jasleen Badesha, Zachary Laksman

Abstract readReview
In one paragraph

Review in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saif DababnehDepartment of Cellular and Physiological Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0003-1593-0756
Arya ArdehaliFaculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0009-0009-1940-9889
Jasleen BadeshaFaculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Zachary LaksmanHeart Rhythm Services & Center for Cardiovascular Innovation, Division of Cardiology, University of British Columbia, 1033 Davie St, Room 200, Vancouver, BC V6E 1M7, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inherited arrhythmias and cardiomyopathies are a group of potentially lethal genetic cardiac disorders which are often passed down through generations and pose risks to several family members. While individually rare, these conditions are collectively common and pose significant challenges for clinical management given their variable severity, age of onset, and response to treatments. Earlier genetic analyses revealed crucial insights into the main genetic culprits of these disorders, such as

Indexed as

Arrhythmias, CardiacCardiomyopathiesGenome-Wide Association StudyGenetic Predisposition to DiseaseHumansMultifactorial InheritanceNAV1.5 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium ChannelBrugada syndromedilated cardiomyopathyGWAShypertrophic cardiomyopathyinherited arrhythmiasinherited cardiomyopathieslong QT syndromepolygenic risk score

Identifiers

PMID41465121
PMCPMC12733222

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.