Evidence mapPaperPMID 41465142Full record

ArticleGenes2025

The Diagnostic Reliability of

Marta Machowska, Jerzy Leszek, Aleksandra Mikołajczyk-Tarnawa, Krystyna Głowacka, Elżbieta Trypka, Małgorzata Rąpała, Janusz Piechota, Anna Wiela-Hojeńska

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marta MachowskaDepartment of Clinical Pharmacology, Wroclaw Medical University, 50-556 Wrocław, Poland.
Jerzy LeszekDepartment of Psychiatry, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Aleksandra Mikołajczyk-TarnawaScreening of Biological Activity Assays and Collection of Biological Material Laboratory, Wroclaw Medical University, 50-556 Wrocław, Poland.
Krystyna GłowackaDepartment of Clinical Pharmacology, Wroclaw Medical University, 50-556 Wrocław, Poland.
Elżbieta TrypkaDepartment of Psychiatry, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Małgorzata RąpałaDepartment of Pediatric Surgery, T. Marciniak Lower Silesian Specialist Hospital, 54-049 Wrocław, Poland.ORCID 0000-0002-2789-5911
Janusz PiechotaAmplicon Ltd., 54-413 Wrocław, Poland.
Anna Wiela-HojeńskaDepartment of Clinical Pharmacology, Wroclaw Medical University, 50-556 Wrocław, Poland.ORCID 0000-0003-3813-2300

Funding

Regional Operational Programme of the Lower Silesian Voivodeship 2014-2020, co-financed by the European Union, European Regional Development Fund RPDS.01.02.01-02-0002/20
6 · The paper itself

Abstract

objectivesAlzheimer's disease (AD) and other dementias represent a growing public health concern, highlighting the need for reliable biomarkers for early diagnosis and treatment monitoring. This study evaluated the potential utility of

methodsThe

resultsA significantly higher frequency of the

conclusionsData on the effects of

Indexed as

Adaptor Proteins, Signal TransducingAlzheimer DiseaseCognitive DysfunctionDementiaMembrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsNuclear ProteinsTumor Suppressor ProteinsAgedAged, 80 and overCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansMaleAdaptor Proteins, Signal TransducingBIN1 protein, humanMembrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsNuclear ProteinsTOMM40 protein, humanTumor Suppressor ProteinsAlzheimer’s diseaseBIN1biomarkersdementiaMCITOMM40

Identifiers

PMID41465142
PMCPMC12732511

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.