Evidence map›Paper›PMID 41465167›Full record

ReviewGenes2025

Gisella Titolo, Mariarosaria Morello, Silvia Caiazza, Ettore Luisi, Achille Solimene, Chiara Serpico, Saverio D'Elia, Paolo Golino, Francesco S Loffredo, Francesco Natale and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gisella TitoloDepartment of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Piazza, Luigi Miraglia, 2, 80138 Naples, Italy.ORCID 0009-0002-7146-7823
Mariarosaria MorelloDepartment of Translational Medical Sciences, Section of Cardiology, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.ORCID 0009-0003-7690-0347
Silvia CaiazzaDepartment of Translational Medical Sciences, Section of Cardiology, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Ettore LuisiDepartment of Translational Medical Sciences, Section of Cardiology, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Achille SolimeneDepartment of Translational Medical Sciences, Section of Cardiology, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Chiara SerpicoDepartment of Translational Medical Sciences, Section of Cardiology, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Saverio D'EliaDepartment of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Piazza, Luigi Miraglia, 2, 80138 Naples, Italy.ORCID 0000-0001-5415-1953
Paolo GolinoDepartment of Translational Medical Sciences, Section of Cardiology, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.ORCID 0000-0002-3590-6983
Francesco S LoffredoDepartment of Translational Medical Sciences, Section of Cardiology, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Francesco NataleVanvitelli Cardiology and Intensive Care Unit, Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0001-7824-6033
Giovanni CimminoDepartment of Translational Medical Sciences, Section of Cardiology, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.ORCID 0000-0002-3802-7052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases represent one of the leading causes of morbidity and mortality worldwide despite tremendous advancements in therapeutic interventions. Prevention remains one of the most effective strategies to reduce individual risk. Apolipoprotein E (ApoE), through its genetic variants (

Indexed as

Apolipoproteins ECardiovascular DiseasesBiomarkersEndothelium, VascularGenotypeHumansPrecision MedicineApoE protein, humanApolipoproteins EBiomarkersApoE genotypeApolipoprotein Ecardiovascular riskendothelial dysfunctionthrombosis

Identifiers

PMID41465167
PMCPMC12732776

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.