ArticleInternational journal of molecular sciences2025
Herbal Composition Inhibits Mitochondrial Oxidative Phosphorylation to Prevent HER2-Positive Breast Cancer and Identifies Potential Active Compounds.
Yi Zhao, Wenxiu Hu, Xinnan Wang, Zhiyue Ren, Yumeng Gong, Lu Liu, Youzhi Sun
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Yi ZhaoResearch Center for Differentiation and Development of Basic Theory of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Wenxiu HuResearch Center for Differentiation and Development of Basic Theory of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Xinnan WangResearch Center for Differentiation and Development of Basic Theory of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Zhiyue RenResearch Center for Differentiation and Development of Basic Theory of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Yumeng GongResearch Center for Differentiation and Development of Basic Theory of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Lu LiuResearch Center for Differentiation and Development of Basic Theory of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Youzhi SunSchool of Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Funding
National Natural Science Foundation of China 82060868, 82360961Natural Science Foundation of Jiangxi Province 20242BAB25562Science and Technology Research Project of Jiangxi Provincial Department of Education GJJ2200907
6 · The paper itselfAbstract
Human Epidermal Growth Factor Receptor 2 (HER2)-positive breast cancer is an aggressive malignancy with limited treatment options. The herbal composition SLC contains
Indexed as
Breast NeoplasmsDrugs, Chinese HerbalErb-b2 Receptor Tyrosine KinasesMitochondriaOxidative PhosphorylationAnimalsCell Line, TumorCell MovementCell ProliferationFemaleHumansMiceMice, NudeSignal TransductionXenograft Model Antitumor AssaysDrugs, Chinese HerbalERBB2 protein, humanErb-b2 Receptor Tyrosine Kinasesactive componentsHER2-positive breast cancermolecular dockingPDK1/PDHA1 signaling pathwaySIRT1/PGC-1α/NRF1/TFAM signaling pathwaysthree herbal compositions SLC
Identifiers
PMID41465397
PMCPMC12733102
What Socratic holds
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