Evidence map›Paper›PMID 41465438›Full record

ArticleInternational journal of molecular sciences2025

Prevalence of Small A-Delta Fiber Neuropathy in Sjögren's Disease: Findings from a Cohort Study.

Magdalena Chylińska, Iga Kościńska-Shukla, Liwia Grudzień, Marta Jaskólska, Adam Wyszomirski, Natalia Dułak, Magdalena Rytlewska, Bartosz Karaszewski

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Magdalena ChylińskaDepartment of Adult Neurology, Medical University of Gdańsk, 80-214 Gdańsk, Poland.ORCID 0000-0002-9374-3430
Iga Kościńska-ShuklaDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdańsk, 80-214 Gdańsk, Poland.ORCID 0000-0001-7821-0671
Liwia GrudzieńDepartment of Adult Neurology, University Clinical Center, 80-214 Gdańsk, Poland.
Marta JaskólskaDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdańsk, 80-214 Gdańsk, Poland.
Adam WyszomirskiDepartment of Adult Neurology, Medical University of Gdańsk, 80-214 Gdańsk, Poland.ORCID 0000-0002-6293-1439
Natalia DułakDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdańsk, 80-214 Gdańsk, Poland.ORCID 0000-0002-1119-6227
Magdalena RytlewskaDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdańsk, 80-214 Gdańsk, Poland.
Bartosz KaraszewskiDepartment of Adult Neurology, Medical University of Gdańsk, 80-214 Gdańsk, Poland.ORCID 0000-0003-2726-0016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyneuropathy is a common condition that limits the quality of life among patients with primary Sjögren disease (pSjD). Somatic sensory fiber neuropathy involving small myelinated (A-δ) and unmyelinated C fibers may precede the development of sicca syndrome. The cutaneous silent period (CSP) is an inhibitory spinal reflex that can be used as a tool for evaluating the dysfunction of A-δ fibers. This study sought to examine CSP parameters, and their correlates, in patients with pSjD vs. healthy controls. We recruited 134 consecutive patients with a diagnosis of pSjD, of whom 109 subjects were included in the analysis. Electrodiagnostic tests comprised a nerve conduction study (NCS) and CSP analysis, alongside laboratory tests and questionnaires (the ESSPRI and SF-36). The examination of the healthy control (HC) group consisted of 113 NCSs and CSP studies. NCS tests of the median nerve in both groups were within the normal range. Statistical analysis revealed a significant difference in CSP duration (

Indexed as

Sjogren's SyndromeSmall Fiber NeuropathyAdultAgedCase-Control StudiesCohort StudiesFemaleHumansMaleMiddle AgedNeural ConductionPrevalencecutaneous silent periodneurophysiologyprimary Sjögren’s diseasesmall fiber neuropathy

Identifiers

PMID41465438
PMCPMC12732339

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.