Evidence map›Paper›PMID 41465462›Full record

ReviewInternational journal of molecular sciences2025

Blood-Based miRNA Panels for Timely Detection of Non-Small-Cell Lung Cancer: From Biomarker Discovery to Clinical Translation.

Yazan Zedan, Maria Yurievna Konoshenko, Olga Evgenievna Bryzgunova, Antonina Aleksandrovna Ilyushchenko, Yaroslava Mikhailovna Danilova, Stanislav Dmitrievich Gorbunkov, Kirill Alekseevich Zykov, Pavel Petrovich Laktionov

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yazan ZedanInstitute of Chemical Biology and Fundamental Medicine Siberian Branch Russian Academy of Sciences ICBFM SB RAS, Academician Lavrentyev Avenue 8, Novosibirsk 630090, Russia.ORCID 0009-0009-4290-4212
Maria Yurievna KonoshenkoInstitute of Chemical Biology and Fundamental Medicine Siberian Branch Russian Academy of Sciences ICBFM SB RAS, Academician Lavrentyev Avenue 8, Novosibirsk 630090, Russia.
Olga Evgenievna BryzgunovaInstitute of Chemical Biology and Fundamental Medicine Siberian Branch Russian Academy of Sciences ICBFM SB RAS, Academician Lavrentyev Avenue 8, Novosibirsk 630090, Russia.ORCID 0000-0003-3433-7261
Antonina Aleksandrovna IlyushchenkoResearch Institute of Pulmonology of the Federal Medical-Biological Agency of the Russian Federation, Orekhoviy Boulevard 28, Moscow 115682, Russia.ORCID 0009-0003-9068-5401
Yaroslava Mikhailovna DanilovaResearch Institute of Pulmonology of the Federal Medical-Biological Agency of the Russian Federation, Orekhoviy Boulevard 28, Moscow 115682, Russia.ORCID 0009-0003-6679-9185
Stanislav Dmitrievich GorbunkovResearch Institute of Pulmonology of the Federal Medical-Biological Agency of the Russian Federation, Orekhoviy Boulevard 28, Moscow 115682, Russia.
Kirill Alekseevich ZykovResearch Institute of Pulmonology of the Federal Medical-Biological Agency of the Russian Federation, Orekhoviy Boulevard 28, Moscow 115682, Russia.ORCID 0000-0003-3385-2632
Pavel Petrovich LaktionovInstitute of Chemical Biology and Fundamental Medicine Siberian Branch Russian Academy of Sciences ICBFM SB RAS, Academician Lavrentyev Avenue 8, Novosibirsk 630090, Russia.

Funding

Russian state-funded project for ICBFM SB RAS 125012900932-4Russian state-funded project for the FBSI "Research Institute of Pulmonology" of the FMBA of Russia 388-03-2024-136
6 · The paper itself

Abstract

Lung cancer (LC) remains a leading cause of global cancer mortality, driving the need for novel timely detection strategies, i.e., stages I-II detection when tumor curation is efficient. Circulating microRNA (miRNAs), with their unique stability in biofluids, offer a powerful approach for non-invasive detection. This review compiles validated miRNAs implicated in the early stages of non-small-cell lung cancer (NSCLC), elucidating their roles in key oncogenic pathways such as epithelial-mesenchymal transition (EMT),

Indexed as

Biomarkers, TumorCarcinoma, Non-Small-Cell LungCirculating MicroRNALung NeoplasmsMicroRNAsEarly Detection of CancerEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansBiomarkers, TumorCirculating MicroRNAMicroRNAsearly stagesLCmiRNAmiRNA panelsNSCLCtimely detection

Identifiers

PMID41465462
PMCPMC12732763

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.