Evidence map›Paper›PMID 41465464›Full record

ArticleInternational journal of molecular sciences2025

Metabolic-Associated Steatotic Liver Disease and FGF21 Dysregulation in Seipin-Deficient and

Silvia Cobelo-Gómez, Lía García-Formoso, Antía Fernández-Pombo, Héctor Lázare-Iglesias, Everardo Díaz-López, Teresa Prado-Moraña, Laura Rodríguez-Sobrino, Ana Senra, David Araújo-Vilar, Sofía Sánchez-Iglesias

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Silvia Cobelo-GómezUETeM-Molecular Pathology Group, Department of Psychiatry, Radiology, Public Health, Nursing and Medicine, Instituto de Investigación Sanitaria Santiago de Compostela-Center for Research in Molecular Medicine and Chronic Diseases (IDIS-CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-0941-626X
Lía García-FormosoUETeM-Molecular Pathology Group, Department of Psychiatry, Radiology, Public Health, Nursing and Medicine, Instituto de Investigación Sanitaria Santiago de Compostela-Center for Research in Molecular Medicine and Chronic Diseases (IDIS-CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-8029-9983
Antía Fernández-PomboUETeM-Molecular Pathology Group, Department of Psychiatry, Radiology, Public Health, Nursing and Medicine, Instituto de Investigación Sanitaria Santiago de Compostela-Center for Research in Molecular Medicine and Chronic Diseases (IDIS-CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-1268-7538
Héctor Lázare-IglesiasDepartment of Pathology, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0003-4646-6423
Everardo Díaz-LópezUETeM-Molecular Pathology Group, Department of Psychiatry, Radiology, Public Health, Nursing and Medicine, Instituto de Investigación Sanitaria Santiago de Compostela-Center for Research in Molecular Medicine and Chronic Diseases (IDIS-CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-5202-638X
Teresa Prado-MorañaUETeM-Molecular Pathology Group, Department of Psychiatry, Radiology, Public Health, Nursing and Medicine, Instituto de Investigación Sanitaria Santiago de Compostela-Center for Research in Molecular Medicine and Chronic Diseases (IDIS-CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0003-2588-7608
Laura Rodríguez-SobrinoUETeM-Molecular Pathology Group, Department of Psychiatry, Radiology, Public Health, Nursing and Medicine, Instituto de Investigación Sanitaria Santiago de Compostela-Center for Research in Molecular Medicine and Chronic Diseases (IDIS-CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0003-1836-1309
Ana SenraCIMUS Biomedical Research Institute, University of Santiago de Compostela-IDIS, 15782 Santiago de Compostela, Spain.ORCID 0000-0003-3541-242X
David Araújo-VilarUETeM-Molecular Pathology Group, Department of Psychiatry, Radiology, Public Health, Nursing and Medicine, Instituto de Investigación Sanitaria Santiago de Compostela-Center for Research in Molecular Medicine and Chronic Diseases (IDIS-CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0003-2852-7851
Sofía Sánchez-IglesiasUETeM-Molecular Pathology Group, Department of Psychiatry, Radiology, Public Health, Nursing and Medicine, Instituto de Investigación Sanitaria Santiago de Compostela-Center for Research in Molecular Medicine and Chronic Diseases (IDIS-CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0003-3887-0573

Funding

Asociación Internacional de Familiares y Afectados de Lipodistrofias (AELIP)Fundación Mutua Madrileña Call 2015Instituto de Salud Carlos III Juan Rodes research contract (JR23/00042)Instituto de Salud Carlos III PI18/01890Instituto de Salud Carlos III PI22/00514Xunta de Galicia ED341b 2017/19Xunta de Galicia ED431B 2020/37
6 · The paper itself

Abstract

Seipin, a protein encoded by the

Indexed as

Fatty LiverFibroblast Growth FactorsGTP-Binding Protein gamma SubunitsHeterotrimeric GTP-Binding ProteinsNon-alcoholic Fatty Liver DiseaseAnimalsDisease Models, AnimalKlotho ProteinsLipid MetabolismLiverMaleMiceMice, KnockoutPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaReceptor, Fibroblast Growth Factor, Type 1Signal TransductionBscl2 protein, mouseFgfr1 protein, mousefibroblast growth factor 21Fibroblast Growth FactorsGTP-Binding Protein gamma SubunitsHeterotrimeric GTP-Binding ProteinsKlb protein, mouseKlotho ProteinsPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mouseReceptor, Fibroblast Growth Factor, Type 1BSCL2CGL2Fgf21liverMASLDPELDseipin

Identifiers

PMID41465464
PMCPMC12732938

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.