Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
16 authors.
Daria ShishkovaDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.ORCID 0000-0002-1518-3888
Victoria MarkovaDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.ORCID 0000-0002-5959-1699
Yulia YurievaDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.ORCID 0009-0007-6734-3787
Alexey FrolovDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.
Anastasia LazebnayaDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.
Maxim SinitskyDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.ORCID 0000-0002-4824-2418
Anna SinitskayaDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.ORCID 0000-0002-4467-8732
Vera MatveevaDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.
Evgenia TorgunakovaDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.
Alexander StepanovDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.
Anna MalashichevaLaboratory of Regenerative Biomedicine, Institute of Cytology of the RAS, 4 Tikhoretskiy Prospekt, 194064 St. Petersburg, Russia.ORCID 0000-0002-0820-2913
Asker KhapchaevLaboratory for Cell Motility, Institute of Experimental Cardiology, National Medical Research Centre of Cardiology Named After Academician E.I. Chazov, 15A Academician Chazov Street, 121552 Moscow, Russia.ORCID 0000-0001-7889-3337
Nikita PodkuychenkoLaboratory for Cell Motility, Institute of Experimental Cardiology, National Medical Research Centre of Cardiology Named After Academician E.I. Chazov, 15A Academician Chazov Street, 121552 Moscow, Russia.
Alexander VorotnikovLaboratory for Cell Motility, Institute of Experimental Cardiology, National Medical Research Centre of Cardiology Named After Academician E.I. Chazov, 15A Academician Chazov Street, 121552 Moscow, Russia.ORCID 0000-0002-1460-971X
Vladimir ShirinskyLaboratory for Cell Motility, Institute of Experimental Cardiology, National Medical Research Centre of Cardiology Named After Academician E.I. Chazov, 15A Academician Chazov Street, 121552 Moscow, Russia.
Anton KutikhinDepartment of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 6 Barbarash Boulevard, 650002 Kemerovo, Russia.ORCID 0000-0001-8679-4857
Funding
Russian Science Foundation 24-65-00039
6 · The paper itself
Abstract
Palmitic acid (PA) is the most common dietary saturated fatty acid, and is abundant in palm and cottonseed oil, butter, and cheese, whereas oleic acid (OA) is a monounsaturated omega-9 fatty acid found in olive oil. The differences in the cytotoxic and pro-inflammatory effects of PA and OA across endothelial cells (ECs) isolated from different vascular beds have not been investigated in detail. Here, we incubated primary human aortic valve (HAVEC), saphenous vein (HSaVEC), internal thoracic artery (HITAEC), and microvascular (HMVEC) ECs with albumin-bound PA or OA for 24 h and found that PA induced a considerable cytotoxic response, accompanied by an elevated expression of the genes encoding cell adhesion molecules (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Palmitic but Not Oleic Acid Induces Pro-Inflammatory Dysfunction of Human Endothelial Cells from Different Vascular Beds In Vitro. · full record | Socratic