Evidence map›Paper›PMID 41465886›Full record

ArticleMedicine2025

The research trends of macrophages in acute kidney injury: A bibliometric analysis.

Xiangyu Zhang, Qiao Zhou, Sizeng Bao, Chengmin Ma, Hanlu Wang, Lingling Bao, Jianwei Ma, Yanping Wang, Jiancheng Huang, Xueyan Bian

Abstract read
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiangyu ZhangDepartment of Nephrology, The First Affiliated Hospital of Ningbo University, Ningbo, China.ORCID 0000-0003-3017-6413
Qiao ZhouDepartment of Nephrology, Huaian Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huaian), Huaian, China.
Sizeng BaoDepartment of Nephrology, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Chengmin MaDepartment of Emergency, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Hanlu WangDepartment of Nephrology, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Lingling BaoDepartment of Nephrology, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Jianwei MaDepartment of Nephrology, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Yanping WangHarvard Center for Polycystic Kidney Disease Research and Renal Division, Brigham and Women's Hospital, Harvard Medical School Boston, Boston, MA.
Jiancheng HuangDepartment of Nephrology, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Xueyan BianDepartment of Nephrology, The First Affiliated Hospital of Ningbo University, Ningbo, China.

Funding

Medical Health Science and Technology Project of Zhejiang Provincial Health Commission 2022KY299Medical Health Science and Technology Project of Zhejiang Provincial Health Commission 2023KY262Medical Health Science and Technology Project of Zhejiang Provincial Health Commission 2024KY304Nature Science Foundation of Ningbo 2023J160
6 · The paper itself

Abstract

objectiveIn recent years, the study of macrophages has gained prominence as a promising avenue for understanding the pathogenesis and therapeutic prospects of acute kidney injury (AKI). In this work, we utilize a bibliometric analysis to map the existing research landscape concerning macrophages in the context of AKI. We aim to provide valuable insights and scholarly references that can facilitate the advancement of comprehensive research and innovation in this field. Our goal is to provide valuable knowledge and academic sources that support the progress of thorough research and breakthroughs in connected fields.

methodsWe incorporated studies focused on macrophages in AKI that were retrieved from the Web of Science Core Collection. All publications were exported in plaintext full-record format and subsequently analyzed using CiteSpace 6.4.R1 for bibliometric evaluation.

resultsA total of 1483 records meeting the inclusion criteria were analyzed. The number of publications in the 1st 12 years was relatively low, but there was a notable increase in publications in 2019 and 2021. The research, encompassing contributions from 56 countries and 437 institutions, is led by China and US Department of Veterans Affairs. The authors with the highest number of publications are Hans-Joachim Anders and Mark D. Okusa, and Bonventre JV was the most frequently cited author. The journal with the highest number of co-citations is Kidney International. Prominent keywords in the literature include macrophages, inflammation, and extracellular vesicles. Keywords extracted from the analysis mainly focus on AKI, expression, acute renal failure, activation, inflammation, and macrophages.

conclusionThis research provides a comprehensive bibliometric evaluation, thereby enhancing our understanding of the current state of macrophage studies in AKI. As a result, it assists both experienced researchers and newcomers by facilitating quick access to crucial information and promoting the extraction of innovative concepts within this specialized field.

Indexed as

Acute Kidney InjuryBibliometricsBiomedical ResearchMacrophagesHumansacute kidney injurybibliometric analysisCiteSpaceferroptosismacrophagessystemic inflammation

Identifiers

PMID41465886
PMCPMC12746999

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.