Evidence mapPaperPMID 41465900Full record

Observational studyMedicine2025

Lipid metabolism in type 1 and type 2 diabetes: A comparative cross-sectional study.

Fatemah Saleh Bin Saleh, Ahmed R Alibrahim, Awad S Alshahrani, Aida Aldughaither, Moeber M Mahzari, Weam S Alharbi, Ghadah B Alanazi

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatemah Saleh Bin SalehDepartment of Family Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Ahmed R AlibrahimDivision of Endocrinology and Metabolism, King Abdulaziz Medical City, Riyadh, Saudi Arabia.ORCID 0000-0001-5389-9433
Awad S AlshahraniDivision of Endocrinology and Metabolism, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Aida AldughaitherDepartment of Family Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Moeber M MahzariDivision of Endocrinology and Metabolism, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Weam S AlharbiDepartment of Family Medicine, Ministry of Health, Riyadh, Saudi Arabia.
Ghadah B AlanaziDepartment of Family Medicine, Ministry of Health, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Types 1 and 2 diabetes mellitus (T1DM and T2DM, respectively) are chronic conditions with distinct pathophysiological mechanisms and clinical manifestations. Dyslipidemia is a common complication in both types, contributing to increased cardiovascular risk. This study aimed to compare the demographic and laboratory characteristics of patients with T1DM and T2DM in Saudi Arabia. We conducted 2 different studies both are retrospective cross-sectional studies that involved 409 T2DM and 509 T1DM patients, respectively. Data were collected from electronic medical records. Clinical characteristics, including diabetes duration, body mass index, hemoglobin A1C levels, and lipid profiles, were analyzed. Statistical comparisons were conducted to identify significant differences between the 2 groups. Patients with T2DM were older (mean age, 58.93 years) than those with T1DM (mean age, 26.15 years). Additionally, substantial demographic differences were observed between the 2 groups. Compared with patients with T2DM, who had hemoglobin A1C levels between 7% to 9%, patients with T1DM had worse glycemic control, with 55.8% of them having such values. Patients with T2DM were more likely to have obesity (63.6%) than those with T1DM (21.8%). Compared with patients with T2DM, those with T1DM had lower triglyceride levels but higher mean low-density lipoprotein, high-density lipoprotein, and total cholesterol levels. A considerably larger proportion of individuals with T2DM had aberrant triglyceride and low high-density lipoprotein levels, indicating a higher incidence of dyslipidemia. Patients with T1DM and T2DM have different clinical characteristics and lipid abnormalities. Patients with T2DM are at higher risk of dyslipidemia and related cardiovascular complications. To reduce cardiovascular risk in patients with diabetes, customized therapies that concentrate on lipid management and glycemic control are necessary. To manage dyslipidemia, further studies are necessary to investigate the underlying mechanisms and develop efficient treatment plans.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2DyslipidemiasLipid MetabolismAdultAgedBody Mass IndexCross-Sectional StudiesFemaleGlycated HemoglobinHumansLipidsMaleMiddle AgedRetrospective StudiesSaudi ArabiaGlycated HemoglobinLipidscardiovascular riskdiabetes mellitusdyslipidemiaglycemic controllipid abnormalities

Identifiers

PMID41465900
PMCPMC12747025

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.