Evidence map›Paper›PMID 41466147›Full record

SynthesisPediatric research2025

An assessment of methods for measuring body composition in full-term infants: A systematic review.

Signe Schiødt, Kathrine V R Hviid, Nina R W Geiker, Karina Banasik, David Westergaard, Henriette S Nielsen

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Pediatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Signe SchiødtDepartment of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark. signe.schioedt@gmail.com.
Kathrine V R HviidDepartment of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Nina R W GeikerCentre for Childhood Health, Copenhagen, Denmark.
Karina BanasikDepartment of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
David WestergaardDepartment of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Henriette S NielsenDepartment of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNumerous methods are available for measuring body composition in infants, however, there is no consensus on which approach is preferred. The aim of this study was to identify one such method for a clinical and research setting.

methodsA systematic search was conducted on PubMed, Embase, and Cochrane Library to identify studies that investigated the accuracy of body composition methods in full-term infants up to 2 years of age.

resultsThirty out of 6643 identified records were included. Several anthropometric equations were investigated with inconsistent results. Dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA) showed more comparable results to those assessed by air displacement plethysmography (ADP), when applying new techniques. Few studies assessed the accuracy of quantitative magnetic resonance (QMR), isotope dilution, and near-infrared spectroscopy (NIR); nonetheless, they all performed well against reference methods. ADP showed agreement compared to deuterium dilution, 3-compartment-, and 4-compartment-models on group-level; however, there were discrepancies when compared to DXA.

conclusionsAnthropometry, DXA, BIA, and ultrasound showed varying results, highlighting the need for further research. QMR, isotope dilution, and NIR appeared promising, but evidence is limited due to few studies. ADP showed consistently small bias compared to multi-component models and isotope dilution. IMPACT: Accurate body composition assessment in infancy has the potential to improve prophylactic actions against obesity. There is relative consensus on the most accurate body composition assessment in pre-term infants in a research setting, however, this consensus has not been available for full-term infants until now. Measure of anthropometry performs with varying precision, suggesting very low feasibility of the method for body composition assessment. From a research perspective, air displacement plethysmography is an accurate method for measuring body composition in full-term infants. This systematic review identifies research gaps within the scientific field of infant body composition.

Identifiers

PMID41466147

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.