Evidence map›Paper›PMID 41466213›Full record

SynthesisBMC women's health2025

Interventions to reduce kinesiophobia in breast cancer patients: a systematic review.

Lingqiao Gong, Panpan Xu, Xue Chen, Hong Tang, Yue Kuang

Abstract readSystematic Review
In one paragraph

Synthesis in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lingqiao GongDepartment of Nursing, Jilin University, Changchun, Jilin, People's Republic of China.
Panpan XuDepartment of Nursing, Jilin University, Changchun, Jilin, People's Republic of China.
Xue ChenDepartment of Nursing, Jilin University, Changchun, Jilin, People's Republic of China. 960546493@qq.com.
Hong TangThe Third Hospital of Jilin University, Changchun, Jilin, People's Republic of China.
Yue KuangRegister Nurse, Daping Hospital, Chongqing, People's Republic of China.

Funding

the Department of Health of Jilin Province 2024A042
6 · The paper itself

Abstract

backgroundKinesiophobia is prevalent in breast cancer (BC) patients, often reducing physical activity and impairing rehabilitation outcomes. A systematic evaluation of interventions targeting kinesiophobia in this population is essential.

objectiveTo assess the characteristics and efficacy of interventions for reducing kinesiophobia in BC patients. DATA SOURCES: We systematically searched seven databases (PubMed, CINAHL, EMBASE, Web of Science, Scopus, Cochrane Library, APA PsycInfo) for English-language studies from inception to May 2025. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Eligible studies included Randomized controlled trials (RCTs), quasi-experimental, and pre/post designs reporting kinesiophobia-related outcomes. Methodological quality was assessed using Joanna Briggs Institute tools.

resultsEight studies (total sample size=404) evaluated seven interventions: pain neuroscience education (PNE) combined with therapeutic exercise (N=3), telerehabilitation-based relaxation (N=1), virtual reality (VR) rehabilitation (N=1), mirror therapy (MT) (N=1), complete decongestive therapy (CDT) (N=1), progressive supervised exercise (N=1), and health education (HE) (N=1). The interventions comprised 10-36 sessions delivered over 6-16 weeks, mostly therapist-delivered. Five studies were high-quality, with only two reporting non-significant effects. Preliminary evidence suggests PNE combined with therapeutic exercise, VR, MT, and progressive exercise may reduce kinesiophobia. However, the efficacy of HE alone, remotely supervised exercise, and CDT remains unclear.

conclusionOverall, the effectiveness of interventions targeting kinesiophobia in BC patients appears to be mixed, and the evidence base for each intervention remains limited. Future studies should prioritize kinesiophobia as a primary outcome and strengthen the evidence through larger sample sizes, extended follow-up periods, and high-quality RCTs.

trial registrationCRD420251060712.

Indexed as

Breast NeoplasmsKinesiophobiaExercise TherapyFemaleHumansRandomized Controlled Trials as TopicBreast cancerFear-AvoidanceFear of movementKinesiophobiaMirror therapyPain neuroscience educationRehabilitationVirtual reality

Identifiers

PMID41466213
PMCPMC12751962

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.